D3648

Diamide

• Synonyme(s) : 1,1′-Azobis(N,N-dimethylformamide), N,N,N′,N′-Tetramethylazodicarboxamide, Azodicarboxylic acid bis(dimethylamide), Diazenedicarboxylic acid bis(N,N-dimethylamide), TMAD
• Formule linéaire : (CH₃)₂NCON=NCON(CH₃)₂
• Numéro CAS: 10465-78-8
• Poids moléculaire : 172.19
• UNSPSC Code: 12352102
• NACRES: NA.22
• PubChem Substance ID: 24278365
• EC Number: 233-951-7
• Beilstein/REAXYS Number: 1910409
• MDL number: MFCD00008318

Propriétés

• assay: ≥98% (TLC)
• Quality Segment: 200
• form: powder
• mp: 113-115 °C
• solubility: water: 19.60-21.00 mg/mL, clear to slightly hazy, orange
• storage temp.: −20°C
• SMILES string: CN(C)C(=O)\N=N\C(=O)N(C)C
• InChI: 1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+
• InChI key: VLSDXINSOMDCBK-BQYQJAHWSA-N

Description

Application

Reported to be of use as a thiol oxidizing agent. Diamide has been used to titrate protein glutathiolation to discriminate from other oxidative protein modifications. Treatment increased protein glutathiolation in a concentration-dependent manner and had comparably little effect on protein-protein disulfide formation.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)