C7039

Cefotaxime sodium salt

powder or crystals, suitable for plant cell culture, BioReagent

• Synonyme(s) : Cefotaxim sodium salt
• Formule empirique (notation de Hill): C₁₆H₁₆N₅NaO₇S₂
• Numéro CAS: 64485-93-4
• Poids moléculaire : 477.45
• Numéro Beilstein : 5711411
• Numéro CE : 264-915-9
• Numéro MDL: MFCD00079073
• Code UNSPSC : 10171502
• ID de substance PubChem : 24892923
• Nomenclature NACRES : NA.72

Propriétés

• product name: Cefotaxime sodium salt, suitable for plant cell culture, BioReagent, powder or crystals
• Gamme de produits: BioReagent
• Niveau de qualité: 200
• Forme: powder or crystals
• Technique(s): cell culture | plant: suitable
• Couleur: off-white to pale yellow
• Solubilité: H₂O: 10% ( )
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Application(s): agriculture
• Mode d’action: cell wall synthesis | interferes
• Température de stockage: 2-8°C
• Chaîne SMILES: [Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O
• InChI: 1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1
• Clé InChI: AZZMGZXNTDTSME-JUZDKLSSSA-M

Description

Description générale

Chemical structure: ß-lactam

Application

Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.

Actions biochimiques/physiologiques

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.

Autres remarques

Broad spectrum third generation cephalosporin antibiotic.

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H317,H334
• Conseils de prudence: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Classification des risques: Resp. Sens. 1 - Skin Sens. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Faceshields, Gloves