77140

Peptidoglycan from Staphylococcus aureus

cell wall component

• Synonyme(s) : Peptidoglycan from S. aureus
• UNSPSC Code: 12352201
• NACRES: NA.32
• MDL number: MFCD00212486

Propriétés

• Quality Segment: 100
• form: lyophilized powder
• solubility: soluble, hazy to turbid, colorless to faintly yellow
• storage temp.: −20°C

Description

Application

Peptidoglycan from Staphylococcus aureus has been used:

• for the stimulation of lymphocytes: peptidoglycan activates the toll-like receptor 2 (TLR2), present in mammalian cells. It works as an antagonist of Poly (I:C)
• for g-type lysozyme stimulation by intraperitoneally inoculating it into sole specimens
• in phosphate buffer saline and injected into Labeo rohita fingerlings, to study its effect on nucleotide-binding oligomerization domain-2 (NOD-2) gene expression

Biochem/physiol Actions

The cell wall of gram positive bacteria is largely made up of peptidoglycan. It is composed of polysaccharide chains interlinked by peptide bridges. This peptidoglycan gives a certain rigidity to the cell wall and gives the cell mechanical strength. It is a surface molecule which is known to stimulate immune reactions including cytokine production to fever.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Major component of the cell wall in gram positive organisms. Consists of a glycan backbone with alternating β 1-4 linked residues of N-acetyl-D-glucosamine and muramic acid. The immunological activities of bacterial peptidoglycans; Peptidoglycan types of bacterial cell walls and their taxonomic implications; Antibody response to peptidoglycan during staphylococcal infections.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)