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15862
Cobalt chloride 0.1 M solution
Synonyme(s) :
Cobalt(II)-chloride solution, Additive Screening Solution 24/Kit-No 78374
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About This Item
Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352302
ID de substance PubChem :
Nomenclature NACRES :
NA.32
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Qualité
for analytical purposes
Niveau de qualité
Densité
1.01 g/mL at 20 °C
Température de stockage
2-8°C
Chaîne SMILES
Cl[Co]Cl
InChI
1S/2ClH.Co/h2*1H;/q;;+2/p-2
Clé InChI
GVPFVAHMJGGAJG-UHFFFAOYSA-L
Application
Actions biochimiques/physiologiques
Cobalt chloride induces hypoxia condition in cells by upregulating hypoxia-inducible factor-1α (HIF-1α), erythropoietin and glycolytic enzymes. It is also responsible for mitochondrial DNA damage in rat neuronal PC12 cells.[3] It is also responsible for the induction of apoptosis.[4]
Cobalt chloride 0.1M solution is an additive screening solution of Additive Screening Kit. Additive Screen kit is designed to allow rapid and convenient evaluation of additives and their ability to influence the crystallization of the sample. The Additive Kit provides a tool for refining crystallization conditions.
Cobalt chloride 0.1M solution is an additive screening solution of Additive Screening Kit. Additive Screen kit is designed to allow rapid and convenient evaluation of additives and their ability to influence the crystallization of the sample. The Additive Kit provides a tool for refining crystallization conditions.
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Aquatic Chronic 2 - Carc. 1B - Repr. 1B
Code de la classe de stockage
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Listes réglementaires
Les listes réglementaires sont principalement fournies pour les produits chimiques. Seules des informations limitées peuvent être fournies ici pour les produits non chimiques. L'absence d'indication signifie qu'aucun des composants n'est répertorié. Il incombe à l'utilisateur de s'assurer de l'utilisation sûre et légale du produit.
EU REACH SVHC Candidate List
CAS No.
EU REACH Annex XVII (Restriction List)
CAS No.
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Les clients ont également consulté
Mitochondrial DNA damage and a hypoxic response are induced by CoCl(2) in rat neuronal PC12 cells.
Wang G, et al.
Nucleic Acids Research, 28, 2135-2135 (2000)
CoCl(2) induces apoptosis via the 18 kDa translocator protein in U118MG human glioblastoma cells.
Zeno S, et al.
Biochemistry, 48, 4652-4652 (2009)
Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans.
Wojtal KA, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 307, G673-G673 (2014)
Francesca Lazzara et al.
Frontiers in pharmacology, 11, 1063-1063 (2020-08-28)
Retinal hypoxia is one of the causative factors of diabetic retinopathy and is also one of the triggers of VEGF release. We hypothesized that specific dysregulated miRNAs in diabetic retinopathy could be linked to hypoxia-induced damage in human retinal endothelial
Exposure to hypoxia following irradiation increases radioresistance in prostate cancer cells.
Hennessey D, et al.
Urologic Oncology, 31, 1106-1106 (2013)
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