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27109

Sigma-Aldrich

Acide citrique

meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance)

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About This Item

Formule linéaire :
HOC(COOH)(CH2COOH)2
Numéro CAS:
77-92-9
Poids moléculaire :
192.12
Numéro Beilstein :
782061
Numéro CE :
201-069-1
Numéro MDL:
MFCD00011669
Code UNSPSC :
12352106
eCl@ss :
39021801
ID de substance PubChem :
329752978
Nomenclature NACRES :
NA.21

Niveau de qualité

200

Pureté

99.5-100.5% (based on anhydrous substance)

Forme

grit

Qualité

anhydrous
meets analytical specification of Ph. Eur., BP, USP, E330

Limite d'explosivité

8 %, 65 °F

Impuretés

residual solvents, complies
≤0.0005% heavy metals (as Pb)
≤0.5% water (Karl Fischer)

Résidus de calcination

≤0.05% (as SO4)

pKa  

(1) 3.13, (2) 4.76, (3) 6.4

Pf

153-159 °C (lit.)

Solubilité

water: 383 g/L at 25 °C

Traces d'anions

chloride (Cl-): ≤50 ppm
oxalate (as oxalic acid): ≤100 ppm
sulfate (SO42-): ≤100 ppm

Traces de cations

As: ≤1 ppm
Ca: ≤200 ppm
Cu: ≤10 ppm
Fe: ≤10 ppm
Hg: ≤1 ppm
Pb: ≤0.5 ppm
Zn: ≤10 ppm

Adéquation

complies for appearance of solution
complies for reaction against H2SO4

Chaîne SMILES 

OC(=O)CC(O)(CC(O)=O)C(O)=O

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

Clé InChI

KRKNYBCHXYNGOX-UHFFFAOYSA-N

Informations sur le gène

human ... SRC(6714)

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Application

Citric acid was used as a test reagent for studying whether the novel pyridazinylpiperazine analog TPRV-1 inhibitor can reduce cough reflex induced by citric acid and capsaicin in guinea pig.

Actions biochimiques/physiologiques

Citric acid in dietary form can augments absorption of aluminium in antacids. It also facilitates the phytoremediation of heavy metal contaminated soil and can transform cadmium into more transportable forms.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319,H335

Classification des risques

Eye Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Acide citrique monohydrate puriss., meets analytical specification of Ph. Eur., BP, USP, E330, 99.5-100.5% (based on anhydrous substance), grit

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P Slanina et al.
Clinical chemistry, 32(3), 539-541 (1986-03-01)
Ten healthy men ingested, twice daily between meals, during each of the seven-day experimental periods: (a) citric acid (as lemon juice), (b) Al(OH)3, or (c) Al(OH)3 + citric acid. Whole blood sampled after each dietary period was analyzed electrothermally after
Y X Chen et al.
Chemosphere, 50(6), 807-811 (2003-04-12)
Adsorption and hydroponics experiments were conducted to study the role of citric acid on the phytoremediation of heavy metal contaminated soil. The results show that addition of citric acid decreased the adsorption of both lead and cadmium, such an effect
Sum Yee Leung et al.
Cough (London, England), 3, 10-10 (2007-12-25)
Cough reflex can be induced by the pepper extract capsaicin and by low pH in guinea-pig airways. Transient receptor potential vanniloid-1 (TPRV-1) is expressed in the sensory and afferent nerve fibres in airways. We hypothesized that a novel pyridazinylpiperazine analog
Maria José Garcia-Fernandez et al.
Biofouling, 29(3), 261-271 (2013-02-27)
Prevention and management of wound infections receive a lot of attention, since the presence of micro-organisms interferes with the wound-healing process. The aim of this work was to use cyclodextrins (CDs) to endow hydrogels and gauzes with the ability to
Konrad Hoetzenecker et al.
European heart journal, 36(11), 676-685 (2013-01-17)
Supernatants of serum-free cultured mononuclear cells (MNC) contain a mix of immunomodulating factors (secretome), which have been shown to attenuate detrimental inflammatory responses following myocardial ischaemia. Inflammatory dilated cardiomyopathy (iDCM) is a common cause of heart failure in young patients.
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