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O0151000

Omeprazole impurity D

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Omeprazole sulfone, 5-Methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl}-1H-benzimidazole, Omeprazole sulphone

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About This Item

Formule empirique (notation de Hill):
C17H19N3O4S
Numéro CAS:
88546-55-8
Poids moléculaire :
361.42
Numéro Beilstein :
8347309
Numéro MDL:
MFCD00869772
Code UNSPSC :
41116107
ID de substance PubChem :
329818824
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

omeprazole

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

O=S(C1=NC2=CC(OC)=CC=C2N1)(CC3=NC=C(C)C(OC)=C3C)=O

InChI

1S/C17H19N3O4S/c1-10-8-18-15(11(2)16(10)24-4)9-25(21,22)17-19-13-6-5-12(23-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)

Clé InChI

IXEQEYRTSRFZEO-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Omeprazole impurity D EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1059

Omeprazole, Pharmaceutical Secondary Standard; Certified Reference Material

1249789

Esomeprazole magnesium, United States Pharmacopeia (USP) Reference Standard

1478505

Omeprazole, United States Pharmacopeia (USP) Reference Standard

O0150000

Omeprazole, European Pharmacopoeia (EP) Reference Standard

Y0001043

Omeprazole magnesium, European Pharmacopoeia (EP) Reference Standard

Y0001042

Omeprazole for peak identification, European Pharmacopoeia (EP) Reference Standard

Y0001028

Esomeprazole magnesium trihydrate, European Pharmacopoeia (EP) Reference Standard

Y0001660

Esomeprazole magnesium dihydrate, European Pharmacopoeia (EP) Reference Standard

1478491

Omeprazole Related Compound F and G mixture, United States Pharmacopeia (USP) Reference Standard

1478516

Omeprazole Related Compound A, United States Pharmacopeia (USP) Reference Standard

1478561

Omeprazole Related Compound I, United States Pharmacopeia (USP) Reference Standard

1478527

Omeprazole Related Compound E, United States Pharmacopeia (USP) Reference Standard

PHR1585

Esomeprazole Magnesium, Pharmaceutical Secondary Standard; Certified Reference Material

1478549

Omeprazole magnesium, United States Pharmacopeia (USP) Reference Standard

PHR1649

Omeprazole Related Compound E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1650

Omeprazole Related Compound I, Pharmaceutical Secondary Standard; Certified Reference Material

1478480

Omeprazole Related Compound B, United States Pharmacopeia (USP) Reference Standard

1478479

R-Omeprazole, United States Pharmacopeia (USP) Reference Standard

BP765

Omeprazole, British Pharmacopoeia (BP) Reference Standard

PHR1988

Omeprazole Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1987

Omeprazole Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1989

Omeprazole Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1954

N′-Methyl Omeprazole, Pharmaceutical Secondary Standard; Certified Reference Material

Y0002075

Esomeprazole sodium, European Pharmacopoeia (EP) Reference Standard

PHR9054

2-Chloromethyl-4-methoxy-3,5-dimethylpyridine hydrochloride, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR2329

Omeprazole Related Compound F and G, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Exclamation markEnvironment
GHS07,GHS09

Mention d'avertissement

Warning

Mentions de danger

H302,H411

Classification des risques

Acute Tox. 4 Oral - Aquatic Chronic 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

W Tassaneeyakul et al.
British journal of clinical pharmacology, 49(2), 139-144 (2000-02-15)
To determine the effect of grapefruit juice on omeprazole metabolism in vivo. This was a randomized crossover study with a 2 week washout period. Omeprazole (20 mg) was taken orally by 13 healthy volunteers after an overnight fast with either
Y Shu et al.
The Journal of pharmacology and experimental therapeutics, 295(2), 844-851 (2000-10-25)
It has been previously reported that omeprazole (OP) oxidation is mediated by CYP2C19 and CYP3A4 in human livers. In this study, we assessed their relative contributions with human liver microsomal fractions from Chinese populations that were genotyped by CYP2C19 and
D S Yim et al.
Journal of chromatography. B, Biomedical sciences and applications, 754(2), 487-493 (2001-05-08)
A column-switching system based on semi-microcolumns was used for direct analysis of omeprazole and omeprazole sulfone in human plasma samples. Plasma samples were injected into a mixed-function (MF Ph-1) column (35 mmx4.6 mm I.D.) to remove proteins and other non-specific
A Abelö et al.
Drug metabolism and disposition: the biological fate of chemicals, 28(8), 966-972 (2000-07-20)
This study demonstrates the stereoselective metabolism of the optical isomers of omeprazole in human liver microsomes. The intrinsic clearance (CL(int)) of the formation of the hydroxy metabolite from S-omeprazole was 10-fold lower than that from R-omeprazole. However, the CL(int) value
Yanhua Zhang et al.
Journal of clinical pharmacology, 46(3), 345-352 (2006-02-24)
To determine the effects of sex and menstrual cycle phase on CYP3A activity and to characterize the intraindividual variability of CYP3A, 24 Caucasian adults were given a single dose of omeprazole every 14th day for 3 months (men) or during
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