M8277

Midodrine hydrochloride

analytical standard, for drug analysis

• Synonyme(s) : (±)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol
• Formule empirique (notation de Hill): C₁₂H₁₈N₂O₄ · HCl
• Numéro CAS: 3092-17-9
• Poids moléculaire : 290.74
• Numéro MDL: MFCD00079455
• Code UNSPSC : 41116107
• ID de substance PubChem : 329818055
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard, for drug analysis
• Niveau de qualité: 100
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• Format: neat
• Chaîne SMILES: Cl.COc1ccc(OC)c(c1)C(O)CNC(=O)CN
• InChI: 1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H
• Clé InChI: MGCQZNBCJBRZDT-UHFFFAOYSA-N
• Informations sur le gène: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

Description

Description générale

Midodrine is a prodrug and a long acting α-adrenergic stimulating agent, and forms an active metabolite, desglymidodrine, which causes an elevation of the systemic blood pressure with the reduction in heart rate.

Application

Midodrine hydrochloride may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

α-Adrenergic agonist; vasoconstrictor

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301
• Conseils de prudence: P301 + P310
• Classification des risques: Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges