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M1824990

Metoclopramide

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide, Methoxychloroprocainamide

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About This Item

Formule empirique (notation de Hill):
C14H22ClN3O2
Numéro CAS:
364-62-5
Poids moléculaire :
299.80
Beilstein:
1884366
Numéro MDL:
MFCD00211338
Code UNSPSC :
41116107
ID de substance PubChem :
329817892
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

metoclopramide

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC

InChI

1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)

Clé InChI

TTWJBBZEZQICBI-UHFFFAOYSA-N

Informations sur le gène

human ... DRD2(1813) , HTR3A(3359) , HTR4(3360)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metoclopramide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1132

Metoclopramide Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1440808

Metoclopramide hydrochloride, United States Pharmacopeia (USP) Reference Standard

M1825010

N,N-Diéthyléthylènediamine, European Pharmacopoeia (EP) Reference Standard

M1825000

Metoclopramide hydrochloride, European Pharmacopoeia (EP) Reference Standard

M1824995

Metoclopramide impurity A, European Pharmacopoeia (EP) Reference Standard

1440820

Metoclopramide Related Compound B, United States Pharmacopeia (USP) Reference Standard

1440841

Metoclopramide Related Compound D, United States Pharmacopeia (USP) Reference Standard

1440819

Metoclopramide Related Compound A, United States Pharmacopeia (USP) Reference Standard

BP357

Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR2283

Metoclopramide Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2284

Metoclopramide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2285

Metoclopramide Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2286

Metoclopramide Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2287

Methyl 4-(Acetylamino)-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2506

Metoclopramide Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2507

Metoclopramide Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2508

Methyl 4-Amino-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

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Certificats d'analyse (COA)

Lot/Batch Number

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James P Reichmann et al.
Managed care (Langhorne, Pa.), 21(5), 44-47 (2012-06-08)
To examine the medical evidence regarding the clinical efficacy and cost-effectiveness of the application of continuous subcutaneous metoclopramide and ondansetron to treat nausea and vomiting during pregnancy. All of the published peer-reviewed articles on the subject were assembled and assigned
Si-Jia Wu et al.
Hepato-gastroenterology, 59(119), 2064-2074 (2012-01-28)
The incidence of postoperative nausea and vomiting is truly high after laparoscopic cholecystectomy. Ondansetron and metoclopramide may be effective in preventing it. Our aim was to estimate the efficacy of ondansetron vs. metoclopramide in preventing postoperative nausea and vomiting after
Terri D Azzopardi et al.
The Annals of pharmacotherapy, 42(3), 397-402 (2008-02-21)
To compare the combination of oral metoclopramide plus an analgesic with oral triptan monotherapy in the treatment of migraine attacks in outpatients. A search of PubMed (1966-October 2007), EMBASE (1974-October 2007), and International Pharmaceutical Abstracts (1970-October 2007) was conducted using
A S Rao et al.
Alimentary pharmacology & therapeutics, 31(1), 11-19 (2009-11-06)
Metoclopramide is a dopamine receptor antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In 2009, the FDA issued a black box warning regarding long-term or high-dose use of this medication
B M Mishriky et al.
British journal of anaesthesia, 108(3), 374-383 (2012-02-07)
Nausea and vomiting occur commonly during and after Caesarean delivery (CD) performed under neuraxial anaesthesia. Metoclopramide is a prokinetic agent reported to be safe in parturients. This meta-analysis assesses the efficacy of metoclopramide for prophylaxis against intra- and postoperative nausea
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