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L0130000

Lactulose

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

4-O-β-D-Galactopyranosyl-D-fructofuranose, 4-O-β-D-Galactopyranosyl-D-fructose

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About This Item

Formule empirique (notation de Hill):
C12H22O11
Numéro CAS:
4618-18-2
Poids moléculaire :
342.30
Numéro Beilstein :
93773
Numéro MDL:
MFCD00151469
Code UNSPSC :
41116107
ID de substance PubChem :
329817343
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

lactulose

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11/c13-1-4-6(16)7(17)8(18)11(21-4)22-9-5(2-14)23-12(20,3-15)10(9)19/h4-11,13-20H,1-3H2/t4-,5-,6+,7+,8-,9-,10+,11+,12+/m1/s1

Clé InChI

JCQLYHFGKNRPGE-WJONTELPSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lactulose EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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4-O-β-Galactopyranosyl-D-mannopyranose ≥98.0% (HPLC)

Sigma-Aldrich

G0886

4-O-β-Galactopyranosyl-D-mannopyranose

Lactulose-13C12 98 atom % 13C, ≥98% (CP)

Sigma-Aldrich

663999

Lactulose-13C12

D-Mannitol European Pharmacopoeia (EP) Reference Standard

M0200000

D-Mannitol

Lactose, Anhydrous Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1025

Lactose, Anhydrous

D-Mannitol meets EP, FCC, USP testing specifications

Sigma-Aldrich

M8429

D-Mannitol

D-Mannitol ≥98% (GC)

Sigma-Aldrich

M4125

D-Mannitol

Edwin R Price et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 164(2), 351-355 (2012-11-21)
Flying vertebrates have been hypothesized to have a high capacity for paracellular absorption of nutrients. This could be due to high permeability of the intestines to nutrient-sized molecules (i.e., in the size range of amino acids and glucose, MW 75-180
C P Kelly et al.
Alimentary pharmacology & therapeutics, 37(2), 252-262 (2012-11-21)
Coeliac disease, an autoimmune disorder triggered by gluten ingestion, is managed by a gluten-free diet (GFD), which is difficult for many patients. Larazotide acetate is a first-in-class oral peptide that prevents tight junction opening, and may reduce gluten uptake and
B Le Nevé et al.
The American journal of gastroenterology, 108(5), 786-795 (2013-04-17)
The aim of the present pilot study was to evaluate the usefulness of a test meal containing lactulose in the non-invasive assessment of visceral sensitivity in irritable bowel syndrome (IBS), and to identify subsets of IBS patients based on gastrointestinal
J Zhao et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(6), 794-802 (2014-03-20)
Small intestinal bacterial overgrowth (SIBO) may be a cause of irritable bowel syndrome (IBS); however, current investigations have important limitations. We aimed to identify clinically relevant diagnostic criteria for SIBO based on lactulose hydrogen breath test (LHBT) alone and combined
Kostan W Reisinger et al.
Journal of pediatric gastroenterology and nutrition, 59(6), 720-724 (2014-08-12)
The incidence of necrotizing enterocolitis (NEC) is higher in formula-fed babies than in breast-fed babies, which may be caused by breast-feeding-induced gut maturation. The effect of breast-feeding on gut maturation has been widely studied in animal models. This study aimed
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