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B0305000

Beclomethasone dipropionate

anhydrous, European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

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About This Item

Formule empirique (notation de Hill):
C28H37ClO7
Numéro CAS:
5534-09-8
Poids moléculaire :
521.04
Numéro MDL:
MFCD00135613
Code UNSPSC :
41116107
ID de substance PubChem :
329773107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard
anhydrous

Famille d'API

beclometasone

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C

InChI

1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1

Clé InChI

KUVIULQEHSCUHY-XYWKZLDCSA-N

Informations sur le gène

human ... NR3C1(2908)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Beclomethasone dipropionate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1048506

Beclomethasone dipropionate, United States Pharmacopeia (USP) Reference Standard

Y0000352

Beclometasone dipropionate for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0000351

Beclometasone dipropionate monohydrate, European Pharmacopoeia (EP) Reference Standard

Y0000469

Beclometasone dipropionate for peak identification, European Pharmacopoeia (EP) Reference Standard

Y0001073

Beclometasone dipropionate impurities F and N, European Pharmacopoeia (EP) Reference Standard

BP030

Beclometasone (beclomethasone) dipropionate, British Pharmacopoeia (BP) Assay Standard

PHR1619

Beclomethasone Dipropionate, Pharmaceutical Secondary Standard; Certified Reference Material

1048517

Beclomethasone Dipropionate Related Compound A, United States Pharmacopeia (USP) Reference Standard

1048543

Beclomethasone Dipropionate Related Compound H, United States Pharmacopeia (USP) Reference Standard

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Warning

Mentions de danger

H361fd,H373

Classification des risques

Repr. 2 - STOT RE 2

Organes cibles

Adrenal gland,Immune system,Bone

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Sarita D Boyd et al.
Journal of acquired immune deficiency syndromes (1999), 63(3), 355-361 (2013-03-29)
To identify an alternative inhaled corticosteroid to fluticasone propionate that can be safely coadministered with HIV protease inhibitors, the safety and pharmacokinetics of beclomethasone dipropionate (BDP) and its active metabolite, beclomethasone 17-monopropionate (17-BMP), in combination with ritonavir (RTV) and darunavir/ritonavir
Jessica K Roberts et al.
The Journal of pharmacology and experimental therapeutics, 345(2), 308-316 (2013-03-21)
Inhaled glucocorticoids, such as beclomethasone dipropionate (BDP), are the mainstay treatment of asthma. However, ≈ 30% of patients exhibit little to no benefit from treatment. It has been postulated that glucocorticoid resistance, or insensitivity, is attributable to individual differences in
Tiago Nunes et al.
Journal of Crohn's & colitis, 7(3), 183-191 (2012-07-13)
IBD is a chronic and relapsing inflammatory disorder of the gut that demands long-lasting treatment targeting both flare-up periods and maintenance of remission. Oral systemic steroids have been used to induce remission in patients with active IBD for over 50
Gail Hayward et al.
The Cochrane database of systematic reviews, 8(8), CD008116-CD008116 (2012-08-17)
The common cold is a frequent illness, which, although benign and self-limiting, results in many consultations to primary care and considerable loss of school or work days. Current symptomatic treatments have limited benefit. Corticosteroids are an effective treatment in other
Linjie Zhang et al.
Respirology (Carlton, Vic.), 18(2), 272-277 (2012-10-09)
Recent studies have raised concerns about the link between use of inhaled corticosteroids (ICS) and risk of pneumonia in patients with chronic obstructive pulmonary disease. This cross-sectional study aimed to investigate the association between ICS and oropharyngeal colonization by Streptococcus
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