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Key Documents

920193

Sigma-Aldrich

Cyrene 2-Methyltetrahydrofuran Blend

greener alternative

BioRenewable, DMF and NMP Substitute

Synonyme(s) :

2-MeTHF Solution, 2-Methyltetrahydrofuran solution, Cyrene solution

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About This Item

Formule empirique (notation de Hill):
C6H8O3
Poids moléculaire :
128.13
Code UNSPSC :
12352212
Nomenclature NACRES :
NA.07

Forme

liquid

Contient

30-80 ppm BHT as stabilizer

Caractéristiques du produit alternatif plus écologique

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

renewable carbon content

100%

Densité

1.153 g/mL

Autre catégorie plus écologique

Description générale

Cyrene 2-Methyltetrahydrofuran Blend with BHT as an inhibitor is specially formulated for use in automated processes and applications where lower viscosity is required, making it easier to handle while maintaining high yields.

This Cyrene blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene nor 2-Methyltetrahydrofuran have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.

This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.
We are committed to bringing you greener alternative products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is BioRenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here for more information.

Application

This cosolvent solution has been shown to have similar reaction yields to NMP and DMF for many cross-coupling reactions, such as:

Caractéristiques et avantages

  • Independently certified as 100% renewable carbon.
  • Closer physical properties of NMP and DMF while maintaining high reaction yields.
  • Sustainably produced and environmentally less hazardous than more traditional petroleum aprotic solvents
  • Both Cyrene and 2-MeTHF are also much safer for handling without the genotoxic concerns of other solvents.
  • It has a lower viscosity than neat Cyrene making it more optimized for automated processes.

Informations légales

CYRENE is a trademark of Circa Group Pvt Ltd

Produit(s) apparenté(s)

Pictogrammes

FlameCorrosion

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2

Risques supp

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Cyrene? blends: a greener solvent system for organic syntheses
Sullivan C, et al.
Green Chemistry, 24, 7184-7193 (2022)
Improved 2-pyridyl reductive homocoupling reaction using biorenewable solvent Cyrene?(dihydrolevoglucosenone)
Webb DA, et al.
RSC Sustainability, 1, 1522-1529 (2023)

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