71480

Sodium diethyldithiocarbamate trihydrate

ACS reagent, for the determination and separation of heavy metals, ≥97%

• Synonyme(s) : Cupral, Diethyldithiocarbamic acid sodium salt
• Formule linéaire : (C₂H₅)₂NCSSNa · 3H₂O
• Numéro CAS: 20624-25-3
• Poids moléculaire : 225.31
• Numéro Beilstein : 3920507
• Numéro CE : 205-710-6
• Numéro MDL: MFCD00150617
• Code UNSPSC : 12000000
• ID de substance PubChem : 57652304
• Nomenclature NACRES : NA.21

Propriétés

• Qualité: ACS reagent; for the determination and separation of heavy metals
• Niveau de qualité: 200
• Densité de vapeur: 5.9 (vs air)
• Pureté: ≥97%
• Forme: powder
• Pf: 95-98.5 °C (lit.)
• Traces de cations: Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; Mn: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• Chaîne SMILES: [H]O[H].[H]O[H].[H]O[H].CCN(CC)C(=S)S[Na]
• InChI: 1S/C5H11NS2.Na.3H2O/c1-3-6(4-2)5(7)8;;;;/h3-4H2,1-2H3,(H,7,8);;3*1H2/q;+1;;;/p-1
• Clé InChI: WWGXHTXOZKVJDN-UHFFFAOYSA-M

Description

Description générale

Sodium diethyldithiocarbamate trihydrate is a chelating agent, generally used in mobilizing toxic metals from the human tissues and experimental animals. It exists as a white or colorless solid, and is freely soluble with gradual decomposition.

Application

Sodium diethyldithiocarbamate trihydrate was used during the synthesis of N-allylpeptides, in a study outlining the strategy to synthesize and purify a hydrogen bond surrogate (HBS) α-helix in ∼1 week.

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO₂ has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Actions biochimiques/physiologiques

Inhibits induction of macrophage nitric oxide synthase.

Autres remarques

Reagent used for the extraction of trace metals into organic solvents for atomic absorption spectroscopy; Precipitation of trace metals for x-ray fluorescence spectroscopy

Informations sur la sécurité

• Pictogrammes: GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H318
• Conseils de prudence: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves