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Key Documents

49779

Sigma-Aldrich

Glycérol

tested according to Ph. Eur., anhydrous

Synonyme(s) :

1,2,3-propanetriol, Glycérine

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About This Item

Formule linéaire :
HOCH2CH(OH)CH2OH
Numéro CAS:
Poids moléculaire :
92.09
Numéro Beilstein :
635685
Numéro CE :
Numéro MDL:
Code UNSPSC :
12191502
ID de substance PubChem :
Nomenclature NACRES :
NA.21

Agence

USP/NF
tested according to Ph. Eur.

Niveau de qualité

Densité de vapeur

3.1 (vs air)

Pression de vapeur

<1 mmHg ( 20 °C)

Forme

liquid

Température d'inflammation spontanée

698 °F

Indice de réfraction

n20/D 1.474 (lit.)

Point d'ébullition

182 °C/20 mmHg (lit.)

Pf

20 °C (lit.)

Densité

1.25 g/mL (lit.)

Chaîne SMILES 

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

Clé InChI

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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Description générale

Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.

Application

Glycerol has been used as
  • a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
  • a fuel during designing enzymatic biofuel cell.
  • a liquid composite matrix with 4-HCCA and 3-amino­quinoline for analysis of neutral and acidic glycans.
  • a matrix for fast atom bombardment MS.
  • may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.

Actions biochimiques/physiologiques

Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

390.2 °F - Pensky-Martens closed cup

Point d'éclair (°C)

199 °C - Pensky-Martens closed cup

Équipement de protection individuelle

Eyeshields, Gloves


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Consulter la Bibliothèque de documents

The mechanism of the protective action of glycerol against haemolysis by freezing and thawing.
J E LOVELOCK
Biochimica et biophysica acta, 11(1), 28-36 (1953-05-01)
Nafiseh Masoumi et al.
Journal of biomedical materials research. Part A, 101(1), 104-114 (2012-07-25)
Microfabricated poly(glycerol sebacate) (PGS) scaffolds may be applicable to tissue engineering heart valve leaflets by virtue of their controllable microstructure, stiffness, and elasticity. In this study, PGS scaffolds were computationally designed and microfabricated by laser ablation to match the anisotropy
Hovsep Mahdessian et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(24), 8913-8918 (2014-06-14)
Genome-wide association studies have identified a locus on chromosome 19 associated with plasma triglyceride (TG) concentration and nonalcoholic fatty liver disease. However, the identity and functional role of the gene(s) responsible for these associations remain unknown. Of 19 expressed genes
Shelley L Forrest et al.
The Journal of comparative neurology, 522(17), 3900-3927 (2014-07-22)
Artemin is a member of the glial cell line-derived neurotrophic factor (GDNF) family that has been strongly implicated in development and regeneration of autonomic nerves and modulation of nociception. Whereas other members of this family (GDNF and neurturin) primarily target
Tian Qiu et al.
Nature communications, 5, 5119-5119 (2014-11-05)
Biological microorganisms swim with flagella and cilia that execute nonreciprocal motions for low Reynolds number (Re) propulsion in viscous fluids. This symmetry requirement is a consequence of Purcell's scallop theorem, which complicates the actuation scheme needed by microswimmers. However, most

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