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Sulfaguanidine

VETRANAL®, analytical standard

Synonyme(s) :

4-Amino-N-(aminoiminomethyl)benzenesulfonamide, 4-Amino-N-guanylbenzenesulfonamide

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About This Item

Formule empirique (notation de Hill):
C7H10N4O2S
Numéro CAS:
Poids moléculaire :
214.24
Numéro Beilstein :
2695326
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

clinical testing

Format

neat

Chaîne SMILES 

NC(=N)NS(=O)(=O)c1ccc(N)cc1

InChI

1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)

Clé InChI

BRBKOPJOKNSWSG-UHFFFAOYSA-N

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Description générale

Chemical structure: sulfonamide
Sulfaguanidine belongs to the sulfonamide class of antibiotics. It can exhibit broad-spectrum inhibition of both gram-positive and gram-negative bacteria.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfaguanidine may be used as an analytical reference standard for the determination of sulfaguanidine in:
  • Food samples of animal origin by salting-out supported liquid extraction (SOSLE) and quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction followed by analysis using nanoflow liquid chromatography high resolution mass spectrometry (LC-HRMS).
  • Bovine muscle samples by hydrophilic interaction liquid chromatography-electrospray-tandem mass spectrometry (HILIC-ESI-MS/MS) equipped with selected reaction monitoring (SRM) mode of detection.
  • Tissues, milk and eggs of food producing animals by ultrasound-assisted extraction (UAE), solid phase extraction (SPE) and LC-MS/MS.
  • Beeswax by solid-liquid extraction (SLE), liquid-liquid extraction (LLE), SPE, QuEChERS extraction and ESI-LC-MS/MS with SRM detection.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3


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Certificats d'analyse (COA)

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Les clients ont également consulté

Determination of sulfonamides in beeswax by liquid chromatography coupled to tandem mass spectrometry.
Mitrowska K and Antczak M
Journal of Chromatography. B, Biomedical Sciences and Applications, 1006, 179-186 (2015)
Matrix-effect free multi-residue analysis of veterinary drugs in food samples of animal origin by nanoflow liquid chromatography high resolution mass spectrometry.
Alcantara-Duran J, et al.
Food Chemistry, 245, 29-38 (2018)
T W Wong et al.
Journal of microencapsulation, 19(4), 511-522 (2002-10-25)
The potential application of pectin as a matrix polymer for making microspheres by an emulsification technique was explored, and the drug release property of these pectinate microspheres containing drug cores of varying aqueous solubilities: sulphanilamide, sulphaguanidine and sulphathiazole, was investigated
Alan D Gift et al.
Journal of pharmaceutical and biomedical analysis, 43(1), 14-23 (2006-08-03)
A moisture sorption gravimetric analyzer has been combined with a Raman spectrometer to better understand the various modes of water-solid interactions relevant to pharmaceutical systems. A commercial automated moisture sorption balance was modified to allow non-contact monitoring of the sample
R F Cross et al.
Journal of chromatography. A, 929(1-2), 113-121 (2001-10-12)
Two electrically neutral analytes previously observed to be separated from the neutral marker in capillary zone electrophoresis (CZE) experiments [sulphanilamide (SAA) and sulphaguanidine (SGW)] have been examined to determine the basis for separation. The degree of separation increases markedly with

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