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Merck
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Key Documents

SCT112

Sigma-Aldrich

BioTracker NIR680 Cytoplasmic Membrane Dye

Live cell imaging lipophilic carbocyanine membrane dye suitable for long-term fluorescent cell labeling and cell tracking studies.

Synonyme(s) :

Live cell imaging probe

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About This Item

Code UNSPSC :
12352207
Nomenclature NACRES :
NA.47

Technique(s)

cell based assay: suitable

Méthode de détection

fluorometric

Conditions d'expédition

ambient

Description générale

Lipophilic carbocyanine dyes are widely used for labeling neurons in tissues by retrograde labeling, and to label membranes in a wide variety of cell types. The dyes are weakly fluorescent in aqueous phase, but become highly fluorescent in lipid bilayers. Staining is highly stable with low toxicity and very little dye transfer in between cells, making the dyes suitable for long-term cell labeling and tracking studies. When live cells are stained, the dyes label plasma membranes and also are taken up into endocytic compartments. Cells can be fixed either before or after staining, although permeabilization affects the staining pattern.

Unlike PKH dyes, BioTracker Cytoplasmic Membrane Dyes do not require a complicated hypoosmotic labeling protocol. They are ready-to-use dye delivery solutions that can be added directly to normal culture media to label suspended or adherent cells in culture.

NIR Cytoplasmic Membrane Dyes are novel near-infrared carbocyanine dyes for labeling the cytoplasmic membranes of living cells. Due to their long emission wavelengths, near-infrared cell membrane stains can be used to label cells for near-infrared small animal imaging studies for non-invasive imaging of cell migration and cell homing.

Spectral Properties
Absorbance: 683nm
Emission: 724nm

Application

Live cell fluorescent imaging
Live cell imaging lipophilic carbocyanine membrane dye suitable for long-term fluorescent cell labeling and cell tracking studies.
Research Category
Cell Imaging
Research Sub Category
Live Cell Dye

Qualité

Spectral Properties
Absorbance: 683nm
Emission: 724nm

Forme physique

Liquid

Stockage et stabilité

Store BioTracker NIR680 Cytoplasmic Membrane Dye at room temp. Protect From Light.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

188.6 °F - (refers to pure substance)

Point d'éclair (°C)

87 °C - (refers to pure substance)


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