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Merck
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Principaux documents

345810

Millipore

G 418 Sulfate, Cell Culture Tested

G418 also known as Geneticin is an aminoglycoside antibiotic related to Gentamicin. Used as a selective agent in transfection of eukaryotic cells. Has highest potency ≥730 µg/mg and purity ≥98%.

Synonyme(s) :

G 418 Sulfate, Cell Culture Tested, G418, G 418, NMD Inhibitor I

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About This Item

Formule empirique (notation de Hill):
C20H40N4O10 · 2H2SO4
Numéro CAS:
Poids moléculaire :
692.71
Numéro MDL:
Code UNSPSC :
12352200

Niveau de qualité

Pureté

≥98% (TLC)

Forme

powder

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze

Impuretés

≤1.0% Ammonia

Couleur

white

Solubilité

water: 100 mg/mL, clear, colorless

Traces de cations

heavy metals: ≤100 ppm

Conditions d'expédition

ambient

Température de stockage

10-30°C

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

Clé InChI

UHEPSJJJMTWUCP-NKCAIAFTSA-N

Description générale

Also available as a sterile-filtered aqueous solution (Cat. No. 345812), a sterile filtered solution in 100 mM HEPES (Cat. No. 508940), and a sterile-filtered solution PBS (Cat. No. 509227).

Avertissement

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, sterilize by filtration through a 0.22 µm or 0.45 µm pore size filter, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short-term storage. Sterile stock solutions are stable for up to 1 year at -20°C.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Health hazard

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Resp. Sens. 1 - Skin Sens. 1

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Wilfried Weber et al.
Methods in molecular biology (Clifton, N.J.), 267, 451-466 (2004-07-23)
Inducible expression of desired transgenes in mammalian cells and animals is a current priority in basic and applied research, biopharmaceutical manufacturing, gene therapy, and tissue engineering, as well as in drug discovery. Among the most prominent human-compatible transgene control technologies
Transgene control engineering in mammalian cells.
Beat P Kramer et al.
Methods in molecular biology (Clifton, N.J.), 308, 123-143 (2005-08-06)
Qin Zhou et al.
Biotechnology journal, 16(9), e2000623-e2000623 (2021-05-31)
Chinese hamster ovary (CHO) cells with a high viable cell density (VCD), resilience to culture stress, and the capacity to continuously express recombinant proteins are highly desirable. Phosphatase and tension homology deleted on chromosome ten (PTEN) functions as a key
Johannes H Hegemann et al.
Methods in molecular biology (Clifton, N.J.), 765, 189-206 (2011-08-05)
Gene inactivation is an essential step in the molecular dissection of gene function. In the yeast Saccharomyces cerevisiae, many tools for gene disruption are available. Gene disruption cassettes comprising completely heterologous marker genes flanked by short DNA segments homologous to
Carlos Barrera-Avalos et al.
iScience, 24(12), 103520-103520 (2021-12-25)
T cell activation requires the processing and presentation of antigenic peptides in the context of a major histocompatibility complex (MHC complex). Cross-dressing is a non-conventional antigen presentation mechanism, involving the transfer of preformed peptide/MHC complexes from whole cells, such as

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