14-778-M
PP5, active
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About This Item
Code UNSPSC :
12352204
eCl@ss :
32160405
Nomenclature NACRES :
NA.32
Produits recommandés
Source biologique
human
Niveau de qualité
Poids mol.
Mw 83.8 kDa
Fabricant/nom de marque
Upstate®
Technique(s)
activity assay: suitable (phosphatase)
Numéro d'accès NCBI
Informations sur le gène
human ... PPP5C(5536)
Description générale
Product Source: N-terminal GST-tagged, recombinant, full length, human PP5, expressed in E. coli cells.
This protein is a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family.
Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine
residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of
this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine
residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of
this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
Conditionnement
Also available in 250μg size as catalog # 14-778M and in bulk as catalog # 14-778-K.
Qualité
Routinely evaluated by the release of phosphate from the substrate 6,8-difluoro-4-methylumbelliferyl phosphate (DiFMUP)
Forme physique
Purified using glutathione agarose.
Autres remarques
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Skin Sens. 1
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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