14-688-M
PKG1α Protein, active, 10 µg
Active, N-terminal 6His-tagged, recombinant, full length PKG1α. For use in Kinase Assays.
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About This Item
Code UNSPSC :
12352202
eCl@ss :
32160405
Nomenclature NACRES :
NA.32
Produits recommandés
Source biologique
human
Niveau de qualité
Produit recombinant
expressed in baculovirus infected Sf21 cells
Poids mol.
Mw 80 kDa
Fabricant/nom de marque
Upstate®
Technique(s)
activity assay: suitable (kinase)
Numéro d'accès NCBI
Numéro d'accès UniProt
Informations sur le gène
human ... PRKG1(5592)
Description générale
N-terminal 6His-tagged, recombinant, full length PKG1α.
Product Source: PKG1α, expressed by baculovirus in Sf21 cells.
Application
Research Category
Inflammation & Immunology
Inflammation & Immunology
Actions biochimiques/physiologiques
Protein Target: PKG1α
Target Sub-Family: AGC
Qualité
routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).
Forme physique
Ni2+/NTA-agarose
Stockage et stabilité
6 months at -70°C from date of shipment
Autres remarques
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Skin Sens. 1
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Mary G Johlfs et al.
PloS one, 10(7), e0132105-e0132105 (2015-07-02)
Profiling cellular proteome is critical to understanding signal integration during cell fate determination. In this study, the capability of capillary isoelectric focusing (cIEF) immunoassays to detect post-translational modifications (PTM) of protein isoforms is demonstrated. cIEF immunoassays exhibit protein detection sensitivity
Modulation of synaptic function by cGMP and cGMP-gated cation channels.
Barnstable, Colin J, et al.
Neurochemistry International, 45, 875-884 (2004)
Sequential activation of soluble guanylate cyclase, protein kinase G and cGMP-degrading phosphodiesterase is necessary for proper induction of long-term potentiation in CA1 of hippocampus. Alterations in hyperammonemia.
Monfort, Pilar, et al.
Neurochemistry International, 45, 895-901 (2004)
Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase.
Birschmann, Ingvild and Walter, Ulrich
Acta Biochimica Polonica, 51, 397-404 (2004)
Zhenyu Li et al.
Cell, 112(1), 77-86 (2003-01-16)
It is currently accepted that cGMP-dependent protein kinase (PKG) inhibits platelet activation. Here, we show that PKG plays an important stimulatory role in platelet activation. Expression of recombinant PKG in a reconstituted cell model enhanced von Willebrand factor (vWF)-induced activation
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