1.00130

Benzoic acid

powder, EMPROVE^® ESSENTIAL, Ph. Eur., BP, USP, E 210

• Synonyme(s) : Benzoic acid, Phenylformic acid, Benzene carboxylic acid
• Formule empirique (notation de Hill): C₇H₆O₂
• Numéro CAS: 65-85-0
• Poids moléculaire : 122.12
• Code UNSPSC : 12352106
• Numéro E: E210
• Numéro de classement CE : 200-618-2

Propriétés

• Agence: BP; Ph. Eur.; USP
• Niveau de qualité: 500
• Pression de vapeur: 0.001 hPa ( 20 °C)
• Gamme de produits: EMPROVE^® ESSENTIAL
• Pureté: 99.5-100.5% substance (anhydrous) basis (acidimetric)
• Forme: powder; solid
• Température d'inflammation spontanée: 570 °C
• Qualité: E 210
• Technique(s): API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• pH: 2.5-3.5 (20 °C in H₂O, saturated solution)
• Point d'ébullition: 249 °C/1013 hPa
• Pf: 121-123 °C
• Température de transition: flash point 121 °C
• Solubilité: water: 2.9 g/L at 25 °C
• Densité: 1.321 g/cm³ at 20 °C
• Traces d'anions: sulfate (SO₄^2-): ≤0.02%
• Traces de cations: As: ≤1 ppm; Cd: ≤10 ppm; Cr: ≤2.5 ppm; Cu: ≤10 ppm; Hg: ≤1 ppm; Mn: ≤25 ppm; Ni: ≤2 ppm; Pb: ≤2 ppm; Zn: ≤10 ppm
• Application(s): liquid formulation; pharmaceutical; semi-solid formulation
• Température de stockage: 15-25°C
• InChI: 1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)
• Clé InChI: WPYMKLBDIGXBTP-UHFFFAOYSA-N

Description

Description générale

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Benzoic acid is typically used as a preservative in pharmaceutical formulations and cosmetics due to its antimicrobial characteristics. It is also used as an additive for the preservation of food.

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H315,H318,H372
• Conseils de prudence: P260 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P314
• Classification des risques: Eye Dam. 1 - Skin Irrit. 2 - STOT RE 1 Inhalation
• Organes cibles: Lungs
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable