Toutes les photos(1)

Principaux documents

COO/COA

Voir toute la documentation

N-905

Nordiazepam solution

Name: Nordiazepam solution
Brand: CERILLIAN

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

Toutes les photos(1)

About This Item

Formule empirique (notation de Hill) :

C₁₅H₁₁ClN₂O

Numéro CAS:

1088-11-5

Poids moléculaire :

270.71

Numéro CE :

200-659-6

Code UNSPSC :

41116107

Nomenclature NACRES :

NA.24

Qualité

certified reference material

Niveau de qualité

300

Forme

liquid

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant^®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

Concentration

1 mg/mL in methanol

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

clinical testing

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES

Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1

InChI

1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)

Clé InChI

AKPLHCDWDRPJGD-UHFFFAOYSA-N

Description générale

Nordiazepam is a benzodiazepine prescribed for treatment of anxiety and panic attacks. This analytical reference standard is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug testing applications. Nordiazepam is also a primary urinary metabolite of benzodiazepines diazepam and chlrodiazepoxide.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit

Description

Tarif

Mention d'avertissement

Danger

Mentions de danger

H225,H301 + H311 + H331,H370

Conseils de prudence

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes,Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup

Listes réglementaires

Les listes réglementaires sont principalement fournies pour les produits chimiques. Seules des informations limitées peuvent être fournies ici pour les produits non chimiques. L'absence d'indication signifie qu'aucun des composants n'est répertorié. Il incombe à l'utilisateur de s'assurer de l'utilisation sûre et légale du produit.

EU REACH Annex XVII (Restriction List)

CAS No.

67-56-1

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

Si vous avez besoin d'assistance, veuillez contacter Service Clients

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Blood drug concentrations of benzodiazepines correlate poorly with actual driving impairment.

Joris C Verster et al.

Sleep medicine reviews, 17(2), 153-159 (2012-08-14)

The use of benzodiazepine receptor agonists can significantly impair driving performance. The aim of this review was to determine if there is a relation between blood concentrations of these drugs and the degree of driving impairment. A literature search was

Simultaneous analysis of diazepam and its metabolites in rat plasma and brain tissue by HPLC-UV and SPE.

Laura Mercolini et al.

Talanta, 80(1), 279-285 (2009-09-29)

Diazepam is frequently used as an adjuvant during antidepressant therapy. Recently, some studies have suggested that the treatment with benzodiazepines could have different efficacy in depressed patients as opposed to non-depressed ones. To clarify the matter, a study is currently

Electronic properties of neuroleptics: ionization energies of benzodiazepines.

Salvatore Millefiori et al.

Journal of molecular modeling, 17(2), 281-287 (2010-05-07)

Vertical ionization energies (VIEs) of medazepam, nordazepam and their molecular subunits have been calculated using the electron propagator method in the P3/CEP-31G* approximation. Vertical electron affinities (VEAs) have been obtained with a ∆SCF procedure at the DFT-B3LYP/6-31+G* level of theory.

Two compartment model of diazepam biotransformation in an organotypical culture of primary human hepatocytes.

Ali Acikgöz et al.

Toxicology and applied pharmacology, 234(2), 179-191 (2008-11-06)

Drug biotransformation is one of the most important parameters of preclinical screening tests for the registration of new drug candidates. Conventional existing tests rely on nonhuman models which deliver an incomplete metabolic profile of drugs due to the lack of

Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report.

David A Fishbain et al.

Pain medicine (Malden, Mass.), 10(3), 565-572 (2008-11-11)

The objectives of this medicolegal case report are the following: 1) to present details of a chronic pain patient (CPP) who was placed on chronic opioid analgesic therapy (COAT), and subsequently overdosed on multiple drugs, some of which were not

Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique