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Principaux documents

M-065

Supelco

(±)-MDEA solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonyme(s) :

(±)-3,4-Methylenedioxyethylamphetamine

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About This Item

Formule empirique (notation de Hill):
C12H17NO2
Numéro CAS:
Poids moléculaire :
207.27
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Niveau de qualité

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

Concentration

1.0 mg/mL in methanol

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

forensics and toxicology

Format

single component solution

Température de stockage

2-8°C

Chaîne SMILES 

CC(CC1=CC=C(OCO2)C2=C1)NCC

InChI

1S/C12H17NO2/c1-3-13-9(2)6-10-4-5-11-12(7-10)15-8-14-11/h4-5,7,9,13H,3,6,8H2,1-2H3

Clé InChI

PVXVWWANJIWJOO-UHFFFAOYSA-N

Catégories apparentées

Description générale

MDEA is an illicit recreational drug of the amphetamine and phenethylamine classes. This analytical reference standard is suitable to use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug testing. A 3,4-methylenedioxy derivative of N-ethylamphetamine, MDEA is abused for its psychedelic effects, similar to those of its structural analog MDMA (Ecstasy).

Application


  • (±)-MDEA Solution for Neurotransmitter Research: Utilized extensively in the study of serotonin release mechanisms, (±)-MDEA-D3 provides a robust tool for examining the biochemical pathways involved in neurotransmitter dynamics, essential for advancements in neuropharmacology (Wen et al., 2024).

  • Racemic MDEA Reagent for Pharmacological Studies: This solution is crucial for the synthesis and pharmacological evaluation of new psychoactive substances, enabling researchers to delineate the metabolic and pharmacodynamic profiles of novel therapeutic agents (Boucenna et al., 2023).

  • High-Purity (±)-MDEA-D3 Reference Material: As a reference standard, this high-purity material is vital for calibrating analytical instruments like LC-MS/MS, ensuring accuracy and reproducibility in quantitative drug analysis and forensic toxicology (Ghorbani et al., 2020).

  • (±)-MDEA-D3 Internal Standard for LC-MS/MS: This deuterated version of MDEA serves as an internal standard in chromatographic analyses, enhancing the precision of quantitative measurements in complex biological matrices (Tian et al., 2021).

  • (±)-MDEA-D3 Solution for Pharmaceutical Cannabinoid Profiling: Employed in cannabinoid biosynthesis research, (±)-MDEA-D3 aids in the profiling and characterization of cannabinoids, supporting the development of cannabis-based pharmaceuticals with targeted therapeutic effects (Irani et al., 2018).


Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

FlameSkull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup


Listes réglementaires

Les listes réglementaires sont principalement fournies pour les produits chimiques. Seules des informations limitées peuvent être fournies ici pour les produits non chimiques. L'absence d'indication signifie qu'aucun des composants n'est répertorié. Il incombe à l'utilisateur de s'assurer de l'utilisation sûre et légale du produit.

EU REACH Annex XVII (Restriction List)

CAS No.

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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Jozef Hritz et al.
Journal of medicinal chemistry, 51(23), 7469-7477 (2008-11-13)
Cytochrome P450s (CYPs) exhibit a large plasticity and flexibility in the active site allowing for the binding of a large variety of substrates. The impact of plasticity and flexibility on ligand binding is investigated by docking 65 known CYP2D6 substrates
R W Romberg et al.
Journal of analytical toxicology, 35(1), 15-22 (2011-01-12)
This study evaluated the potential for partial separation of drugs from their deuterated internal standards using Cerex(®) Polycrom™ CLIN II solid-phase extraction (SPE) cartridges. After elution from the column and derivatization, gas chromatography-mass spectrometry results showed that the target compound
Emily Joy Jaehne et al.
Psychopharmacology, 201(2), 161-170 (2008-08-06)
3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") disrupts thermoregulation in rats and can lead to life-threatening hyperthermia in humans. MDMA administration can also lead to long-term neurotoxicity in animals and possibly humans. The purpose of the current study was to extend previous results on
Tsadik T Abraham et al.
Journal of analytical toxicology, 33(8), 439-446 (2009-10-31)
3,4-Methylenedioxymethamphetamine (MDMA), or ecstasy, is excreted as unchanged drug, 3,4-methylenedioxyamphetamine (MDA), and free and glucuronidated/sulfated 4-hydroxy-3-methoxymethamphetamine (HMMA), and 4-hydroxy-3-methoxyamphetamine (HMA) metabolites. The aim of this paper is to describe the pattern and timeframe of excretion of MDMA and its metabolites
Peter R Stout et al.
Journal of analytical toxicology, 34(8), 430-443 (2010-01-01)
On November 25, 2008, the U.S. Department of Health and Human Services posted a final notice in the Federal Register authorizing the use of liquid chromatography-tandem mass spectrometry (LC-MS-MS) and other technologies in federally regulated workplace drug testing (WPDT) programs.

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