860076W

C18:0 GM1-d5

Avanti Research^™ - A Croda Brand 860076W, methanol solution

• Synonyme(s) : C18:0 GM1 Ganglioside-d5 (synthetic, ammonium salt)
• Formule empirique (notation de Hill): C₇₃H₁₂₉D₅N₄O₃₁
• Numéro CAS: 2260669-93-8
• Poids moléculaire : 1568.88
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Pureté: >99% (TLC)
• Forme: methanol solution
• Conditionnement: pkg of 1 × 1 mL (860076W-100ug)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 860076W
• Concentration: 0.1 mg/mL
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC([2H])(C([2H])([2H])[2H])[2H])=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C3)[C@H]2O)O[C@@H]4O[C@H](C

Description

Description générale

Gangliosides are glycosphingolipids, contains one or more residues of sialic acid. They are grouped according to the number of their sialic acid residues: one (M), two (D), or three (T). The GM1 ganglioside denotes a glycolipid that contains a monosialylated tetraose oligosaccharide (Galβ1 & 3GalNAcβ1 & 4(NeuAcα2 & 3)Galβ1 & 4Glcβ1 & 1′Cer). C18:0 GM1 ganglioside contains stearic acid as one of the fatty acid chain. These are normal components of the plasma membranes of mammalian cells and are abundant in neuronal membranes. Structurally, they possess the oligosaccharide chain constituting the hydrophilic portion in the extracellular medium and the ceramide moiety constituting the hydrophobic portion in the lipid layer of the membrane. The length and degree of unsaturation of both alkyl chains present in the ganglioside influences membrane fluidity and permeability. The ceramide portion regulates the activity of membrane-associated proteins.

Actions biochimiques/physiologiques

Gangliosides plays an important role in cell-cell recognition, cell adhesion, contact inhibition, and tissue differentiation. GM1 ganglioside binds the cholera toxin.

Conditionnement

2 mL Amber Glass Sealed Ampule

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes,Central nervous system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 49.5 °F
• Point d'éclair (°C): 9.7 °C