857120P

14:0 Lyso PA

1-myristoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder

• Synonyme(s) : 1-tetradecanoyl-sn-glycero-3-phosphate (sodium salt); PA(14:0/0:0); 14:0 LPA; 110677
• Formule empirique (notation de Hill) : C₁₇H₃₄O₇PNa
• Numéro CAS: 325465-45-0
• Poids moléculaire : 404.41
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Essai: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 25 mg (857120P-25mg); pkg of 1 × 500 mg (857120P-500mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 857120P
• Type de lipide: phospholipids; cardiolipins
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C17H35O7P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(19)23-14-16(18)15-24-25(20,21)22;/h16,18H,2-15H2,1H3,(H2,20,21,22);/q;+1/p-1/t16-;/m1./s1
• Clé InChI: HGENTPHNTSLRPB-PKLMIRHRSA-M

Description

Description générale

Lysophosphatidic acid (LPA) belongs to a class of phospholipids, that has a glycerol backbone attached by a phosphate group, an aliphatic chain and a hydroxyl group. It has a phosphate group attached to sn-3 position, an aliphatic chain attached to sn-1 or sn-2 position and the hydroxyl group attached to the remaining sn-1 or sn-2 position.

Application

14:0 Lyso PA is suitable to use as internal standard to spike serum samples for the extraction of serum lipids. It is also suitable to use as standard lipids for extraction of lipids and for quality control in multiple reaction monitoring (MRM) assay.

Actions biochimiques/physiologiques

Lysophosphatidic acid (LPA) participates in several biological functions. It acts as a potential biomarker for detecting ovarian cancer. LPA stimulates platelet aggregation, smooth muscle contraction, chemotaxis, cytoskeleton rearrangement, Ca²⁺ mobilization, neurotransmitter release and cell proliferation.

Conditionnement

20 mL Clear Glass Screw Cap Vial (857120P-500mg)

5 mL Amber Glass Screw Cap Vial (857120P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids