850345C

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine, chloroform

• Synonyme(s) : 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine; DMPC; PC(14:0/14:0)
• Formule empirique (notation de Hill): C₃₆H₇₂NO₈P
• Numéro CAS: 18194-24-6
• Poids moléculaire : 677.93
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Pureté: >99% (TLC)
• Forme: liquid
• Conditionnement: pkg of 1 × 2.5 mL (850345C-25mg); pkg of 1 × 20 mL (850345C-500mg); pkg of 2 × 20 mL (850345C-1g); pkg of 2 × 4 mL (850345C-200mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 850345C
• Concentration: 10 mg/mL (850345C-25mg); 25 mg/mL (850345C-1g); 25 mg/mL (850345C-200mg); 25 mg/mL (850345C-500mg)
• Type de lipide: phospholipids; cardiolipins
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• InChI: 1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m0/s1
• Clé InChI: CITHEXJVPOWHKC-UMSFTDKQSA-N

Description

Description générale

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

14:0 PC (DMPC) has been used in liposome preparation. It is also suitable for use:

• in the preparation of lipid bicelles for nuclear magnetic resonance (NMR) experiments
• in labeled vesicle preparation for fluorescence polarization measurements
• as internal standard (IS) for the quantitation of phosphatidylcholine (PC) by liquid chromatography with tandem mass spectrometry (LC-MS-MS)

Actions biochimiques/physiologiques

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Conditionnement

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-1g)

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-500mg)

5 mL Clear Glass Sealed Ampule (850345C-200mg)

5 mL Clear Glass Sealed Ampule (850345C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Conseils de prudence: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organes cibles: Central nervous system, Liver,Kidney
• Code de la classe de stockage: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): does not flash
• Point d'éclair (°C): does not flash