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840039P

Avanti

18:0-18:1 PS

1-stearoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

Synonyme(s) :

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); SOPS; PS(18:0/18:1(9Z)); 110672

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About This Item

Formule empirique (notation de Hill):
C42H79NO10PNa
Numéro CAS:
321883-23-2
Poids moléculaire :
812.04
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Essai

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 10 mg (840039P-10mg)
pkg of 2 × 100 mg (840039P-200mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 840039P

Type de lipide

phospholipids
cardiolipins

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H80NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,38-39H,3-17,19,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b20-18-;/t38-,39+;/m1./s1

Clé InChI

ALPKKMIPHGSQRX-NJZWBUMZSA-M

Description générale

18:0-18:1 PS (1-stearoyl-2-oleoyl-sn-glycero-3-phospho-L-serine) is a sodium salt of a modified lipid which has phosphoserine as the backbone.

Application

18:0-18:1 PS (1-stearoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)):
  • has been used in the preparation of multilamellar and unilamellar liposomes
  • may be used in the preparation of liposomes for liposome binding assays
  • may be used to generate multilamellar phospholipid vesicles

Actions biochimiques/physiologiques

Phosphatidylserine (PS) plays a key role in protein kinase C pathways.

Conditionnement

5 mL Clear Glass Sealed Ampule (840039P-10mg)
5 mL Clear Glass Sealed Ampule (840039P-200mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Souvent commandé avec ce produit

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

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Lot/Batch Number

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Consulter la Bibliothèque de documents

Katarzyna Gajos et al.
Analytical and bioanalytical chemistry, 409(4), 1109-1119 (2016-11-09)
Among the various biomarkers that are used to diagnose or monitor disease, extracellular vesicles (EVs) represent one of the most promising targets in the development of new therapeutic strategies and the application of new diagnostic methods. The detection of circulating
Anne Jäkel et al.
Protein & cell, 1(2), 188-197 (2011-01-05)
The role of surfactant protein A (SP-A) in the recognition and clearance of apoptotic cells is well established, but to date, it is still not clear which surface molecules of apoptotic cells are involved in the process. Here we present
Kristof Schutters et al.
Apoptosis : an international journal on programmed cell death, 15(9), 1072-1082 (2010-05-05)
Cells are able to execute apoptosis by activating series of specific biochemical reactions. One of the most prominent characteristics of cell death is the externalization of phosphatidylserine (PS), which in healthy cells resides predominantly in the inner leaflet of the
Julie K Freed et al.
Endothelium : journal of endothelial cell research, 15(4), 225-230 (2008-07-30)
Previous studies have demonstrated that endothelial cells exposed to laminar shear stress are protected from apoptotic stimuli such as tumor necrosis factor (TNF)-alpha. The authors investigated the role of phosphatidylserine (PS) in this phenomenon. Western blot analysis of cleaved caspase
John M Harrington et al.
The Journal of biological chemistry, 289(36), 24811-24820 (2014-07-20)
Haptoglobin-related protein (Hpr) is a component of a minor subspecies of high density lipoproteins (HDL) that function in innate immunity. Here we show that assembly of Hpr into HDL is mediated by its retained N-terminal signal peptide, an unusual feature
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