W266418

(S)-(−)-Perillyl alcohol

≥95%, FG

• Synonyme(s) : p-Mentha-1,8-diene-7-ol
• Formule empirique (notation de Hill): C₁₀H₁₆O
• Numéro CAS: 18457-55-1
• Poids moléculaire : 152.23
• Numéro FEMA: 2664
• Conseil de l'Europe Nº : 2024
• Numéro MDL: MFCD00062995
• Code UNSPSC : 12164502
• ID de substance PubChem : 24901225
• Numéro Flavis : 2.060
• Nomenclature NACRES : NA.21

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 400
• Qualité: FG; Halal; Kosher
• Conformité réglementaire: EU Regulation 1334/2008 & 178/2002; FDA 21 CFR 117; FDA 21 CFR 172.515
• Pureté: ≥95%
• Activité optique: [α]20/D −88°, c = 1 in methanol
• Indice de réfraction: n20/D 1.501 (lit.)
• Point d'ébullition: 119-121 °C/11 mmHg (lit.)
• Densité: 0.96 g/mL at 25 °C (lit.)
• Application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• Allergène alimentaire: no known allergens
• Propriétés organoleptiques: fatty; green
• Chaîne SMILES: CC(=C)[C@H]1CCC(CO)=CC1
• InChI: 1S/C10H16O/c1-8(2)10-5-3-9(7-11)4-6-10/h3,10-11H,1,4-7H2,2H3/t10-/m1/s1
• Clé InChI: NDTYTMIUWGWIMO-SNVBAGLBSA-N

Description

Application

• CYP108N12 initiates p-cymene biodegradation in Rhodococcus globerulus.: This study explores the enzymatic breakdown pathways of monoterpenes, using (S)-(−)-Perillyl alcohol as a precursor, offering insights into microbial degradation processes that could be vital for bioremediation efforts or synthetic biology applications (Giang et al., 2022).


• Orofacial antinociceptive effects of perillyl alcohol associated with codeine and its possible modes of action.: Research demonstrates the pain-relieving properties of (S)-(−)-Perillyl alcohol when combined with codeine, highlighting its potential for developing new analgesic formulations in dental and facial pain management (Limeira et al., 2022).


• Orofacial antinociceptive activity of (S)-(-)-perillyl alcohol in mice: a randomized, controlled and triple-blind study.: This study underpins the effectiveness of (S)-(−)-Perillyl alcohol in reducing orofacial pain in a controlled experimental setup, providing a basis for further clinical trials in pain management (Tomaz-Morais et al., 2017).


• In Vivo Anti-Tumor Activity and Toxicological Evaluations of Perillaldehyde 8,9-Epoxide, a Derivative of Perillyl Alcohol.: Highlights the anti-tumor properties of a novel derivative of (S)-(−)-Perillyl alcohol, suggesting its potential as a therapeutic agent in oncology, with comprehensive studies on its efficacy and safety (Andrade et al., 2016).

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 230.0 °F - closed cup
• Point d'éclair (°C): 110 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter