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Merck
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Principaux documents

W224502

Sigma-Aldrich

Carvacrol

≥98%, FCC, FG

Synonyme(s) :

5-Isopropyl-2-methylphenol

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About This Item

Formule linéaire :
(CH3)2CHC6H3(CH3)OH
Numéro CAS:
Poids moléculaire :
150.22
Numéro FEMA:
2245
Numéro Beilstein :
1860514
Numéro CE :
Conseil de l'Europe Nº :
2055
Numéro MDL:
Code UNSPSC :
12164502
ID de substance PubChem :
Numéro Flavis :
4.031
Nomenclature NACRES :
NA.21

Source biologique

synthetic

Niveau de qualité

Qualité

FG
Fragrance grade
Halal
Kosher

Agence

follows IFRA guidelines
meets purity specifications of JECFA

Conformité réglementaire

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

Pureté

≥98%

Indice de réfraction

n20/D 1.522 (lit.)

Point d'ébullition

236-237 °C (lit.)

Pf

3-4 °C (lit.)

Densité

0.976 g/mL at 20 °C (lit.)

Application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

Allergène alimentaire

no known allergens

Allergène de parfum

no known allergens

Propriétés organoleptiques

camphoraceous; woody; spicy

Chaîne SMILES 

CC(C)c1ccc(C)c(O)c1

InChI

1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3

Clé InChI

RECUKUPTGUEGMW-UHFFFAOYSA-N

Informations sur le gène

human ... UGT1A4(54657)

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Description générale

Carvacrol is a monoterpene compound that can be used as a flavoring agent in food and cosmetics. It is one of the major volatile components in oregano essential oil.

Application


  • Carvacrol and Thymol Hybrids: Potential Anticancer and Antibacterial Therapeutics.: This review explores the synthesis, characterization, and biological activities of carvacrol and thymol hybrids, highlighting their potential as anticancer and antibacterial agents. The study emphasizes the significance of these compounds in developing novel therapeutic strategies (Peter et al., 2024).

  • Essential Oil Constituents as Anti-Inflammatory and Neuroprotective Agents: An Insight through Microglia Modulation.: This review investigates the role of essential oil constituents, including carvacrol, in modulating microglial activity. The findings suggest significant anti-inflammatory and neuroprotective effects, providing insights into their potential therapeutic applications in neuroinflammatory diseases (Stojanović et al., 2024).

  • Evidence of the Protective Role of Carvacrol in a Retinal Degeneration Animal Model.: This study demonstrates the protective effects of carvacrol in a retinal degeneration model. The results indicate that carvacrol can mitigate retinal damage and preserve retinal function, suggesting its potential as a therapeutic agent for retinal diseases (Inda et al., 2024).


Clause de non-responsabilité

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Pictogrammes

CorrosionExclamation markEnvironment

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

>212.0 °F

Point d'éclair (°C)

> 100 °C

Équipement de protection individuelle

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Les clients ont également consulté

Antimicrobial activity of carvacrol: current progress and future prospectives
Nostro A & Papalia T
Recent Patents on Anti-Cancer Drug Discovery, 7(1), 28-35 (2012)
The natural antimicrobial carvacrol inhibits Campylobacter jejuni motility and infection of epithelial cells
Van Alphen LB, et al
PLoS ONE, 7(9), e45343-e45343 (2012)
Rachel Spiering et al.
PloS one, 7(9), e46336-e46336 (2012-10-11)
Tolerogenic dendritic cells (DCs) can induce regulatory T cells and dampen pathogenic T cell responses. Therefore, they are possible therapeutic targets in autoimmune diseases. In this study we investigated whether mouse tolerogenic DCs are induced by the phytonutrient carvacrol, a
Laura Higueras et al.
Carbohydrate polymers, 97(2), 262-268 (2013-08-06)
The aim of this work was to design new polymer-based systems exhibiting an adjustable loading capacity of carvacrol depending on the film formulation. For this purpose, biocomposite films were developed employing chitosan (CS) as the polymer matrix and hydroxypropyl-β-cyclodextrins (HP-βCDs)
Bo Tang et al.
Oncogene, 38(20), 3946-3961 (2019-01-30)
Although VPAC1 and its ligand vasoactive intestinal peptide (VIP) are important in gastrointestinal physiology, their involvements in progression of gastrointestinal tumor have not been explored. Here, we found that higher expression of VIP/VPAC1 was observed in gastric cancer compared to

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