D152609
2,2-Dimethylbutyric acid
96%
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About This Item
Formule linéaire :
C2H5C(CH3)2CO2H
Numéro CAS:
Poids moléculaire :
116.16
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
Produits recommandés
Niveau de qualité
Pureté
96%
Forme
liquid
Indice de réfraction
n20/D 1.4154 (lit.)
Point d'ébullition
94-96 °C/5 mmHg (lit.)
Densité
0.928 g/mL at 25 °C (lit.)
Chaîne SMILES
CCC(C)(C)C(O)=O
InChI
1S/C6H12O2/c1-4-6(2,3)5(7)8/h4H2,1-3H3,(H,7,8)
Clé InChI
VUAXHMVRKOTJKP-UHFFFAOYSA-N
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
174.2 °F - closed cup
Point d'éclair (°C)
79 °C - closed cup
Équipement de protection individuelle
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Les clients ont également consulté
N Uchiyama et al.
European journal of drug metabolism and pharmacokinetics, 16(3), 189-196 (1991-07-01)
Metabolic pathways of simvastatin (MK-733), a lactone prodrug of an inhibitor of HMG-CoA reductase, were elucidated in male rats, using the [14C]-labelled compound. Evidence has been obtained for hydrolysis of simvastatin and its metabolites at their 2,2-dimethylbutyryl moieties. Metabolites identified
Bridgette Wilson et al.
The American journal of gastroenterology, 115(6), 906-915 (2020-05-21)
The low FODMAP diet (LFD) reduces symptoms and bifidobacteria in irritable bowel syndrome (IBS). β-galactooligosaccharides (B-GOS) may reduce the symptoms and increase bifidobacteria in IBS. We investigated whether B-GOS supplementation alongside the LFD improves IBS symptoms while preventing the decline
Suthat Fucharoen et al.
British journal of haematology, 161(4), 587-593 (2013-03-28)
β-thalassaemia intermedia (BTI) syndromes cause haemolytic anaemia, ineffective erythropoiesis, and widespread complications. Higher fetal globin expression within genotypes reduces globin imbalance and ameliorates anaemia. Sodium 2,2 dimethylbutyrate (HQK-1001), an orally bioavailable short-chain fatty acid derivative, induces γ-globin expression experimentally and
Abdullah Kutlar et al.
American journal of hematology, 88(11), E255-E260 (2013-07-06)
2,2-Dimethylbutyrate (HQK-1001), an orally-bioavailable promoter-targeted fetal globin gene-inducing agent, was evaluated in an open-label, randomized dose-escalation study in 52 subjects with hemoglobin SS or S/β(0) thalassemia. HQK-1001 was administered daily for 26 weeks at 30 mg/kg (n = 15), 40
Abdullah Kutlar et al.
American journal of hematology, 87(11), 1017-1021 (2012-08-14)
Therapeutics which reduce the pathology in sickle cell syndromes are needed, particularly noncytotoxic therapeutics. Fetal hemoglobin (HbF, α(2) γ(2) ) is established as a major regulator of disease severity; increased HbF levels correlate with milder clinical courses and improved survival.
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