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Key Documents

926574

Sigma-Aldrich

Upconversion Nanoparticles

NaYF4,Yb,Tm@NaYF4,Yb,Nd, PEG-COOH modified core-shell, fluorescence λex 808 nm, blue light

Synonyme(s) :

UCNPs

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About This Item

Code UNSPSC :
12352302
Nomenclature NACRES :
NA.23

Niveau de qualité

100

Concentration

2 mg/mL in water

Groupe de la matrice active

PEG-COOH surface treatment

Taille des particules

30-40 nm

Fluorescence

λex 808 nm (blue)
λem 365 nm
λem 450 nm
λem 470 nm

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Application

Upconversion nanoparticles (UCNPs), are the result of a unique optical process in which near-infrared (NIR) light excitation is converted into visable and/or UV emission. Upconversion (UC) utilizes sequential absorption of multiple photons utilizing both lifetime and real ladder-like energy levels of ions in a host lattice to produce a higher energy anti-Stokes luminescence.

This optical features of UCNPs, results in deep tissue penetration and minimal autofluorescence background, for a broad range of applications of UCNP in diagnostics and biomedical imaging systems.

Applications include:

Fluorescent microscopy
Deep-tissue bioimaging
Nanomedicine
Optogenetics
Security labelling
Volumetric display

Informations légales

Product of RuixiBiotechCo.Ltd

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

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Certificats d'analyse (COA)

Lot/Batch Number
MKCV9716
MKCS7748

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Consulter la Bibliothèque de documents

Shihui Wen et al.
Nature communications, 9(1), 2415-2415 (2018-06-22)
Lanthanide-doped upconversion nanoparticles (UCNPs) are capable of converting near-infra-red excitation into visible and ultraviolet emission. Their unique optical properties have advanced a broad range of applications, such as fluorescent microscopy, deep-tissue bioimaging, nanomedicine, optogenetics, security labelling and volumetric display. However
Daniel J Gargas et al.
Nature nanotechnology, 9(4), 300-305 (2014-03-19)
Imaging at the single-molecule level reveals heterogeneities that are lost in ensemble imaging experiments, but an ongoing challenge is the development of luminescent probes with the photostability, brightness and continuous emission necessary for single-molecule microscopy. Lanthanide-doped upconverting nanoparticles overcome problems
Christoph Drees et al.
Angewandte Chemie (International ed. in English), 55(38), 11668-11672 (2016-08-12)
Upconversion nanoparticles (UCNPs) convert near-infrared into visible light at much lower excitation densities than those used in classic two-photon absorption microscopy. Here, we engineered <50 nm UCNPs for application as efficient lanthanide resonance energy transfer (LRET) donors inside living cells. By
Upconversion nanoparticles: design, nanochemistry, and applications in theranostics.
Guanying Chen et al.
Chemical reviews, 114(10), 5161-5214 (2014-03-13)
Yujia Liu et al.
Nature, 543(7644), 229-233 (2017-02-23)
Lanthanide-doped glasses and crystals are attractive for laser applications because the metastable energy levels of the trivalent lanthanide ions facilitate the establishment of population inversion and amplified stimulated emission at relatively low pump power. At the nanometre scale, lanthanide-doped upconversion

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