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Merck
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918741

Sigma-Aldrich

TissueFab® bioink 

(Gel)ma -VIS/405nm, low endotoxin

Synonyme(s) :

Bioink, GelMA, Gelatin methacrylamide, Gelatin methacrylate, Gelatin methacryloyl

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About This Item

Code UNSPSC :
12352201
Nomenclature NACRES :
NA.23

Niveau de qualité

100

Description

suitable for 3D bioprinting applications
with LAP photoinitiator

Stérilité

sterile-filtered

Forme

viscous liquid

Impuretés

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)
<50 EU/mL Endotoxin

Couleur

colorless to pale yellow

Taille des particules

0.2 μm

pH

6.5-7.5

Application(s)

3D bioprinting

Température de stockage

2-8°C

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Application

TissueFab® GelMA-Vis-LAP bioink is a gelatin methacryloyl (GelMA) based bioink for 3D bioprinting applications. LAP is used as the photoinitiator, which allows blue light photocrosslinking of the printed structure. The formulation is optimized for high printing fidelity and cell viability. The low endotoxin level of this product is lower than 50 EU/mL.

Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications. The addition of photocrosslinkable methacrylamide functional groups in GelMA allows the synthesis of biocompatible, biodegradable, and non-immunogenic hydrogels that are stable in biologically relevant conditions and promote cell adhesion, spreading, and proliferation.

Informations légales

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number
MKCP7147

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Y Shi et al.
Biomedical materials (Bristol, England), 13(3), 035008-035008 (2018-01-09)
Three-dimensional bioprinting is an emerging technology for fabricating living 3D constructs, and it has shown great promise in tissue engineering. Bioinks are scaffold materials mixed with cells used by 3D bioprinting to form a required cell-laden structure. In this paper
B Duan et al.
Acta biomaterialia, 10(5), 1836-1846 (2013-12-18)
Tissue engineering has great potential to provide a functional de novo living valve replacement, capable of integration with host tissue and growth. Among various valve conduit fabrication techniques, three-dimensional (3-D) bioprinting enables deposition of cells and hydrogels into 3-D constructs
Wanjun Liu et al.
Biofabrication, 10(2), 024102-024102 (2017-11-28)
Bioinks with shear-thinning/rapid solidification properties and strong mechanics are usually needed for the bioprinting of three-dimensional (3D) cell-laden constructs. As such, it remains challenging to generate soft constructs from bioinks at low concentrations that are favorable for cellular activities. Herein
P Selcan Gungor-Ozkerim et al.
Biomaterials science, 6(5), 915-946 (2018-03-02)
Bioprinting is an emerging technology with various applications in making functional tissue constructs to replace injured or diseased tissues. It is a relatively new approach that provides high reproducibility and precise control over the fabricated constructs in an automated manner
Wanjun Liu et al.
Advanced healthcare materials, 6(12) (2017-05-04)
Bioprinting is an emerging technique for the fabrication of 3D cell-laden constructs. However, the progress for generating a 3D complex physiological microenvironment has been hampered by a lack of advanced cell-responsive bioinks that enable bioprinting with high structural fidelity, particularly
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