712191

COMU^®

≥96.5% (TLC), for peptide synthesis

• Synonyme(s) : (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate
• Formule empirique (notation de Hill): C₁₂H₁₉F₆N₄O₄P
• Numéro CAS: 1075198-30-9
• Poids moléculaire : 428.27
• Numéro MDL: MFCD11975052
• Code UNSPSC : 12352107
• ID de substance PubChem : 329763117
• Nomenclature NACRES : NA.22

Propriétés

• product name: COMU^®, 97%
• Niveau de qualité: 100
• Pureté: ≥96.5% (TLC); 96.5-103.5% (T); 97%
• Forme: crystals
• Capacité de réaction: reaction type: Coupling Reactions
• Caractéristiques du produit alternatif plus écologique: Less Hazardous Chemical Syntheses; Inherently Safer Chemistry for Accident Prevention; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• Application(s): peptide synthesis
• Groupe fonctionnel: amine; ester; ether; nitrile
• Autre catégorie plus écologique: , Aligned
• Température de stockage: 2-8°C
• Chaîne SMILES: F[P-](F)(F)(F)(F)F.CCOC(=O)C(=NO\C(N1CCOCC1)=[N+](/C)C)C#N
• InChI: 1S/C12H19N4O4.F6P/c1-4-19-11(17)10(9-13)14-20-12(15(2)3)16-5-7-18-8-6-16;1-7(2,3,4,5)6/h4-8H2,1-3H3;/q+1;-1/b14-10-;
• Clé InChI: GPDHNZNLPKYHCN-DZOOLQPHSA-N

Description

Description générale

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a Safer, non-explosive and more effective replacement for Benzotriazole-Based peptide coupling reagents and thus aligns with "Less Hazardous Chemical Synthesis" and "Inherently Safer Chemistry for Accident Prevention". Click here for more information.

Application

COMU – Safer and More Efficient Peptide Coupling Reagent

Advantages

• Equal or even superior performance to HATU
• Non-explosive (does not contain benzotriazole moiety)
• Suitable for solution phase & solid phase peptide synthesis
• Utmost retention of configuration – low to non-existent racemization
• High solubility and stability in typical solvents
• Visual or colorimetric reaction monitoring possible
• Easy removal of water-soluble by-products

Morpholine-Based Immonium and Halogenoamidinium Salts as Coupling Reagents in Peptide Synthesis

Informations légales

COMU is a registered trademark of Luxembourg Bio Technologies Ltd.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves