20019AST
Astec® CYCLOBOND I 2000 Chiral (5 μm) HPLC Columns
L × I.D. 15 cm × 2.1 mm, HPLC Column
Synonym(s):
CYCLOBOND I 2000 Cyclodextrin-Based Chiral Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
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product name
Astec® CYCLOBOND I 2000 Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 2.1 mm
material
stainless steel column
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-50 °C temperature
172 bar pressure (2500 psi)
technique(s)
HPLC: suitable
LC/MS: suitable
L × I.D.
15 cm × 2.1 mm
matrix
silica particle platform
matrix active group
cyclodextrin, beta- phase
particle size
5 μm
pore size
100 Å
operating pH
3.5-7
separation technique
chiral
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General description
CYCLOBOND I 2000 is bonded with β-cyclodextrin by a patented process to produce a stable matrix with the cyclodextrin arranged in such a way as to retain its most valuable property of forming inclusion complexes. This allows them to effect numerous chemical separations by selectively including into their cavities a wide variety of organic molecules. Non-inclusion type separations are also possible with the polar organic mode for a wide variety of molecule types.
Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature
- Bonded phase: Underivatized, native β-cyclodextrin
Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature
Application
- Thioether bridged cationic cyclodextrin stationary phases: Effect of spacer length, selector concentration and rim functionalities on the enantioseparation.: This study investigates the effect of different variables on the enantioseparation efficiency of thioether bridged cationic cyclodextrin stationary phases, utilizing the Astec CYCLOBOND 2000 Chiral HPLC Column for the separation processes (Li et al., 2016).
- Enantiomeric separations of illicit drugs and controlled substances using cyclofructan-based (LARIHC) and cyclobond I 2000 RSP HPLC chiral stationary phases.: This research explores the use of cyclobond I 2000 RSP HPLC chiral stationary phases, including Astec CYCLOBOND 2000, in the enantiomeric separation of various illicit drugs and controlled substances (Padivitage et al., 2014).
- Screening approach, optimisation and scale-up for chiral liquid chromatography of cathinones.: The paper discusses a screening approach and optimization methods for chiral liquid chromatography of cathinones, highlighting the application of Astec CYCLOBOND 2000 Chiral HPLC Column in these processes (Perera et al., 2012).
- Stereoselective analysis of hydroxybupropion and application to drug interaction studies.: This study focuses on the stereoselective analysis of hydroxybupropion using chiral stationary phases, including Astec CYCLOBOND 2000, to explore drug interaction effects (Xu et al., 2007).
- Solid-phase extraction of methadone enantiomers and benzodiazepines in biological fluids by two polymeric cartridges for liquid chromatographic analysis.: This research investigates the extraction and analysis of methadone enantiomers and benzodiazepines in biological fluids using the Astec CYCLOBOND 2000 Chiral HPLC Column for effective separation (He et al., 2005).
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
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Chiral separation of 3-phenyl-3-(2-pyridyl)propylamines, and analogous guanidines and guanidine-N-carboxylic acid esters with high-performance liquid chromatography and capillary zone electrophoresis
Schuster, Andreas, et al.
Journal of Chromatography A, 793 (1), 77-90 (1998)
High-performance liquid chromatography of diastereomeric flavanone glycosides in Citrus on a ?-cyclodextrin-bonded stationary phase (Cyclobond I)
Krause, Martin; Galensa, Rudolf
Journal of Chromatography A, 588 (1-2), 41-45 (1991)
Liquid chromatographic resolution of enantiomers of deltahedral carborane and metallaborane derivatives
Plesek, Jaromir, et al.
Journal of Chromatography A, 626 (2), 197-206 (1992)
High-performance liquid chromatographic determination of ibuprofen, its metabolites and enantiomers in biological fluids
Geisslinger, G., et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 491, 139-149 (1989)
A F Casy et al.
Journal of pharmaceutical and biomedical analysis, 9(10-12), 787-792 (1991-01-01)
The interaction of beta-cyclodextrin with a series of structurally related chiral thromboxane antagonists was investigated using NMR and RP-HPLC. HPLC studies used both a cyclodextrin bonded phase (Cyclobond I), and beta-cyclodextrin as a mobile phase additive with an achiral C8
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