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M7891

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

BioReagent, for silylations, LiChropur

Synonym(s):

N-Trimethylsilyl-N-methyl trifluoroacetamide, MSTFA

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About This Item

Linear Formula:
CF3CON(CH3)Si(CH3)3
CAS Number:
Molecular Weight:
199.25
UNSPSC Code:
12352111
NACRES:
NA.25
PubChem Substance ID:
EC Number:
246-331-6
Beilstein/REAXYS Number:
1941550
MDL number:
Form:
liquid
Pricing and availability is not currently available.
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vapor density

>1 (vs air)

Quality Segment

vapor pressure

8.8 mmHg ( 27 °C)

product line

BioReagent

form

liquid

quality

for silylations, LiChropur

reaction suitability

reaction type: Silylations, reagent type: derivatization reagent

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.38 (lit.)

bp

130-132 °C (lit.)

solubility

chloroform: soluble 0.1 mg/mL

density

1.07 g/mL at 25 °C (lit.), 1.075 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C

InChI

1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3

InChI key

MSPCIZMDDUQPGJ-UHFFFAOYSA-N

General description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide(MSTFA) is a BioReagent commonly used for silylation reactions in analyticalchemistry.

Application

N-Methyl-N-(trimethylsilyl)trifluoroacetamide can be used:
  • In the derivatization step of the metabolomics analysis using gas chromatography/mass spectrometry (GC/MS).
  • Derivatization reagent in gas chromatography with flame ionization detection (GC-FID) analysis.

Packaging

Sealed ampules contain 1 ml. Gram sizes are in screw-cap bottles.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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6947939486669478
reaction suitability

reaction type: Silylations, reagent type: derivatization reagent

reaction suitability

-

reaction suitability

-

reaction suitability

-

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

solubility

chloroform: soluble 0.1 mg/mL

solubility

-

solubility

-

solubility

-

refractive index

n20/D 1.38 (lit.)

refractive index

n20/D 1.38 (lit.), n20/D 1.380

refractive index

n20/D 1.38 (lit.)

refractive index

n20/D 1.378

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

form

liquid

form

liquid

form

liquid

form

liquid


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pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

77.0 °F - closed cup

flash_point_c

25 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Response of Downy Oak (Quercus pubescens Willd.) to climate change: Transcriptome assembly, differential gene analysis and targeted metabolomics
Mevy JP, et al.
Plants (Basel, Switzerland), 9(9), 1149-1149 (2020)
A gas chromatography-mass spectrometry-based whole-cell screening assay for target identification in distal cholesterol biosynthesis
Muller C, et al.
Nature Protocols, 14(8), 2546-2570 (2019)
Hee-Kyung Jeon et al.
Journal of chromatography. A, 1131(1-2), 192-202 (2006-08-08)
A novel method has been developed to simultaneously determine and quantify seven organic UV filters employing liquid (solid)-liquid extraction, derivatization with N-methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) and gas chromatography with mass spectrometric detection in various environmental matrices. The UV filters determined were:



Global Trade Item Number

SKUGTIN
M7891-1ML04061834062448
M7891-10X1ML04061838258540
M7891-5G04061837684968
M7891-10AMP04061837684937
M7891-25G04061837684951
M7891-1AMP04061837684944

Questions

  1. If I order this reagent in solid form, then how am I supposed to reconstitute it? I mean, with which reagent and to what concentration?

    1 answer
    1. This product is a neat or pure liquid. The compound is not available in solid form. The material is soluble in chloroform at 0.1 mg/mL.

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