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A1752

Adenosine 5′-monophosphate sodium salt

≥99%, from yeast, powder

Synonym(s):

5′-Adenylic acid, A-5′-P, AMP

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About This Item

Empirical Formula (Hill Notation):
C10H14N5O7P · xNa+ · yH2O
CAS Number:
Molecular Weight:
347.22 (anhydrous free acid basis)
MDL number:
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.51
Assay:
≥99%
Biological source:
yeast
Form:
powder
Solubility:
H2O: soluble
Storage temp.:
−20°C
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Product Name

Adenosine 5′-monophosphate sodium salt, from yeast, ≥99%

biological source

yeast

Quality Segment

assay

≥99%

form

powder

solubility

H2O: soluble

storage temp.

−20°C

SMILES string

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@]((COP(O)(O)=O)([H])O3.C.

Application

Adenosine 5′-monophosphate sodium salt has been used:
  • as a component of reactivation medium to reactivate mouse sperm extracted from caudae epididymides for sperm motility studies [1]
  • as a substrate in signal amplification by reversible exchange (SABRE) method to develop biocompatible SABRE hyperpolarization[2]
  • as a substrate in wheat and Aspergillus niger phytase, assay
  • in luciferase assay to monitor intracellular α-synuclein oligomerization in S1S2 cells[3]
  • to study its effects on induction of therapeutic hypothermia and neuronal damage in a rat model of cardiac arrest (CA) and resuscitation[4]

Biochem/physiol Actions

Adenosine 5′-monophosphate (5′-AMP) is used to enhance flavor in meat and poultry soups. It is also used as a food additive for specific nutritional purposes.[5] 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). [6] Along with inosine monophosphate (IMP), AMP mediates the dissociation of skeletal muscle actomyosin to actin and myosin. Therefore, these two factors may be involved in causing the resolution of rigor mortis in muscles.[7]

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This Item
A2252A9272A0386
biological source

yeast

biological source

yeast

biological source

yeast

biological source

yeast

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥99%

assay

≥97%

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: soluble

solubility

1 M NH4OH: soluble 50 mg/mL, clear, colorless, H2O: soluble (with addition of mild alkali)

solubility

1 N NH4OH: 50 mg/mL, clear, colorless

solubility

water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

  1. Are there any known phosphate-containing derivatives or contaminants in this product?

    1 answer
    1. The product has the phosphate containing material including free inorganic phosphate from breakdown.

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