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Key Documents

900915

Sigma-Aldrich

N-Azidoacetylgalactosamine-tetraacylated

Synonym(s):

Ac4GalNAz

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About This Item

Empirical Formula (Hill Notation):
C16H22N4O10
CAS Number:
Molecular Weight:
430.37
UNSPSC Code:
12352116
NACRES:
NA.22

form

powder or crystals

Quality Level

reaction suitability

reaction type: click chemistry

storage temp.

−20°C

Application

N-Azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) provides the first part of a simple and robust two-step technique that helps identify and characterize cell surface sialic acid-containing glycoproteins. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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