Skip to Content
Merck
All Photos(1)

Documents

793248

Sigma-Aldrich

Polyhydroxylated fullerenes, water soluble

Synonym(s):

C60(OH)n, water soluble C60, Fullerenols, Polyhydroxy fullerenes

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C60(OH)n · mH2O (n>40, m>8)
UNSPSC Code:
12352103
NACRES:
NA.23

form

solid

Quality Level

100

color

light yellow to yellow

solubility

water: soluble >50 mg/mL
DMSO: slightly soluble
methanol: slightly soluble

storage temp.

2-8°C

Related Categories

General description

Polyhydroxylated fullerenes, (water soluble)(PHF) is a functionalized fullerene that is also called fullerenol which can be used as a molecular anti-oxidant and a nanoparticle. It is a non-toxic fullerene which is attached with 12-42 hydroxyl groups per molecule that result in water solubility. Its structure and the position of the hydroxyl groups will depend on the existing pH of the media.

Application

PHF may be incorporated in titanium dioxide to form a nanocomposite which can be potentially used in the photocatalysis of semiconductors. Its photothermal and therapeutic properties may be used in non-invasive image based therapy of cancer.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Yasukazu Saitoh et al.
Journal of photochemistry and photobiology. B, Biology, 102(1), 69-76 (2010-10-15)
Polyhydroxylated fullerenes (fullerenols: C(60)(OH)(n)) are known as the major water-soluble fullerene derivatives which possess particular significance as free radical scavengers or antioxidants in biological systems. Recently, the novel polyhydroxylated fullerene (C(60) (OH)(44)·8H(2)O: SHH-F) was successfully synthesized. In the present study
Synthesis and Biological Activity of Fullerenols with Various Contents of Hydroxyl Groups
Eropkin YM, et al.
Pharmaceutical Chemistry Journal, 47(2), 87-91 (2013)
Yunxiang Sun et al.
Nanoscale, 11(24), 11933-11945 (2019-06-13)
Featuring small sizes, caged structures, low cytotoxicity and the capability to cross biological barriers, fullerene hydroxy derivatives named fullerenols have been explored as nanomedicinal candidates for amyloid inhibition. Understanding the surface chemistry effect of hydroxylation extents and the corresponding amyloid
Facile and scalable synthesis of a highly hydroxylated water-soluble fullerenol as a single nanoparticle
Kokubo K, et al.
Nano Research, 4(2), 204-215 (2011)
Yasukazu Saitoh et al.
Molecular and cellular biochemistry, 366(1-2), 191-200 (2012-04-03)
Reactive oxygen species has been suggested to be one of the key factors associated with the development of obesity. During spontaneous differentiation of mouse stromal preadipocytes OP9 into adipocytes, intracellular superoxide anion radicals (O (2) (-.) ) level markedly increases
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service