703907

RuCl(p-cymene)[(R,R)-Ts-DPEN]

• Synonym(s): [N-[(1R,2R)-2-(Amino-κN)-1,2-diphenylethyl]-4-methylbenzenesulfonamidato-κN]chloro[(1,2,3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene]-ruthenium
• Empirical Formula (Hill Notation): C₃₁H₃₅ClN₂O₂RuS
• CAS Number: 192139-92-7
• Molecular Weight: 636.21
• MDL number: MFCD10567385
• UNSPSC Code: 12352116
• PubChem Substance ID: 329762075
• NACRES: NA.22

Properties

• form: powder
• optical activity: [α]20/D −116°, c = 0.1 in chloroform
• mp: 215 °C
• storage temp.: 2-8°C
• SMILES string: CC(C)c1ccc(C)cc1.Cc2ccc(cc2)S(=O)(=O)N([Ru]Cl)[C@@H]([C@H](N)c3ccccc3)c4ccccc4
• InChI: 1S/C21H21N2O2S.C10H14.ClH.Ru/c1-16-12-14-19(15-13-16)26(24,25)23-21(18-10-6-3-7-11-18)20(22)17-8-4-2-5-9-17;1-8(2)10-6-4-9(3)5-7-10;;/h2-15,20-21H,22H2,1H3;4-8H,1-3H3;1H;/q-1;;;+2/p-1/t20-,21-;;;/m1.../s1
• InChI key: AZFNGPAYDKGCRB-AGEKDOICSA-M

Description

General description

RuCl(p-cymene)[(R,R)-Ts-DPEN] is a chiral diamine ligand complexed with ruthenium.

Application

Takasago Ligands and Complexes for Asymmetric Reactions

Phosphine cationic ruthenium catalysts used for enantioselective hydrogenation of:

• Quinolines
• N-Alkyl ketimines
• Antitumor and antiproliferative derivatives of natural products isolated from bacteria
• Hydroxy arylaldehydes via Rap-Stoermer-enantioselective transfer hydrogenation

Catalyst with improved performance modified via microenvironment engineering of nanocages

Legal Information

Sold in collaboration with Takasago for research purposes only. WO9720789

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves