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655422

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QuadraPure® TU

macroporous, 400-600 μm particle size

Synonym(s):

QuadraPure® Thiourea

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About This Item

MDL number:
UNSPSC Code:
12163800
PubChem Substance ID:
NACRES:
NA.22

reaction suitability

reagent type: catalyst
reagent type: chelator

particle size

400-600 μm

General description

QuadraPure® TU is a thiourea-based metal scavenger resin that can be used to prevent metal contamination that occurs during pharmaceutical or fine chemical processing.

Application

Metal Scavenger: Pd, Pt, Ru, Rh, Au, Ag, Cu, Hg, Pb, Cd, Ni, Co, Fe, V, Zn
QuadraPure® TU has been used to remove color from the solution due to leaching of copper species during the copper(I)-mediated 1,2,3-triazole formation via [3+2] cycloaddition of acetylenic compounds with azides. It has also been used as a modifier for carbon pastes to develop QuadraPure® TU residue functionalized resin-modified carbon paste electrode (“TUR-CPE”) for the determination of Pb(II) ions.
Other applications include the removal of metal ions like copper and palladium that leach out during continuous flow coupling reactions.

Legal Information

QuadraPure is a registered trademark of Johnson Matthey Finland Oy

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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[3+ 2] Cycloaddition of acetylenes with azides to give 1, 4-disubstituted 1, 2, 3-triazoles in a modular flow reactor.
Smith CD, et al.
Organic & Biomolecular Chemistry, 5(10), 1559-1561 (2007)
Paolo Tosatti et al.
The Journal of organic chemistry, 76(13), 5495-5501 (2011-05-14)
The sequential use of Cu-catalyzed asymmetric allylic alkylation, olefin cross-metathesis, and Ir-catalyzed asymmetric allylic amination allows the concise, stereodivergent synthesis of complex chiral amines with complete regiocontrol and good diastereoselectivity, exemplified by the synthesis of a pair of diastereoisomeric unnatural
Continuous flow ligand-free Heck reactions using monolithic Pd [0] nanoparticles.
Nikbin N, et al.
Organic Process Research & Development, 11(3), 458-462 (2007)
Michael J. Girgis, et al.
Organic Process Research & Development, 12, 1209-1217 (2008)
Continuous flow coupling and decarboxylation reactions promoted by copper tubing.
Zhang Y, et al.
Organic Letters, 13(2), 280-283 (2010)

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