477028

2-Hydroxyethyl methacrylate

≥99%, contains ≤50 ppm monomethyl ether hydroquinone as inhibitor

• Synonym(s): 1,2-Ethanediol mono(2-methylpropenoate), Glycol methacrylate, HEMA
• Linear Formula: CH₂=C(CH₃)COOCH₂CH₂OH
• CAS Number: 868-77-9
• Molecular Weight: 130.14
• Beilstein: 1071583
• MDL number: MFCD00002863
• UNSPSC Code: 12162002
• PubChem Substance ID: 24871325
• NACRES: NA.23

Properties

• vapor density: 5 (vs air)
• vapor pressure: 0.01 mmHg ( 25 °C)
• Assay: ≥99%
• contains: ≤50 ppm monomethyl ether hydroquinone as inhibitor
• refractive index: n20/D 1.453 (lit.)
• bp: 67 °C/3.5 mmHg (lit.)
• density: 1.073 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CC(=C)C(=O)OCCO
• InChI: 1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3
• InChI key: WOBHKFSMXKNTIM-UHFFFAOYSA-N

Description

General description

2-Hydroxyethyl methacrylate (HEMA) is biocompatible in nature. Polymeric hydrogel scaffold can be produced by polymerizing HEMA in water.

Application

A polymeric hydrogel for drug delivery. Patent has been applied for the development of artificial cornea or KPro, it is composed of pHEMA (polymerized from HEMA) and poly (methyl methacrylate)(PMMA). HEMA may be used as a macromonomer for the synthesis of 2-hydroxyethylmethacrylate-poly(ε-caprolactone) (HEMA-PCL) by coordinated anionic ring opening polymerization (ROP). 

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H317,H319
• Precautionary Statements: P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 222.8 °F - closed cup
• Flash Point(C): 106 °C - closed cup