470864

Bromine

≥99.99% trace metals basis

• Synonym(s): Dibromine
• Empirical Formula (Hill Notation): Br₂
• CAS Number: 7726-95-6
• Molecular Weight: 159.81
• EC Number: 231-778-1
• MDL number: MFCD00010896
• UNSPSC Code: 12352101
• PubChem Substance ID: 24870690
• NACRES: NA.22

Properties

• vapor density: 7.14 (vs air)
• vapor pressure: 175 mmHg ( 20 °C); 671 mmHg ( 55 °C)
• Assay: ≥99.5% (by Na₂S₂O₃, titration); ≥99.99% trace metals basis
• resistivity: 7.8E18 μΩ-cm, 20°C
• impurities: ≤0.001% I₂; ≤0.001% S compounds; <100 ppm total metallic impurities
• evapn. residue: ≤0.005%
• bp: 58.8 °C (lit.)
• mp: −7.2 °C (lit.)
• density: 3.119 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.05%
• cation traces: Ni: ≤5 ppm; heavy metals: ≤2 ppm
• SMILES string: BrBr
• InChI: 1S/Br2/c1-2
• InChI key: GDTBXPJZTBHREO-UHFFFAOYSA-N

Description

Application

Bromine can be used as a brominating and oxidizing agent in chemical synthesis.
It can be used:

• To brominate alkylbenzenes at the benzylic position using photocatalytic conditions.
• To prepare brominated aromatic compounds by electrophilic aromatic substitution reactions in the presence of Lewis acid catalysts.
• For the bromination of carbonyl compounds at a carbonyl group via Hell-Volhard-Zelinski reaction in the presence of phosphorus trihalides.
• To prepare isocyanates, carbamates, or amines by reacting with primary amides in the presence of base via Hofmann rearrangement.

Other Notes

Contains organic bromine compounds

Safety Information

• Pictograms: GHS06,GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H314,H330,H400
• Precautionary Statements: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1A
• Storage Class Code: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves