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An efficient synthesis of 1α,25-dihydroxy-20-epi-vitamin D3.

The Journal of steroid biochemistry and molecular biology (2013-02-12)
R Fraga, B López-Pérez, K Sokolowska, A Guini, T Regueira, S Díaz, A Mouriño, M A Maestro
ZUSAMMENFASSUNG

The synthesis of 1α,25-dihydroxy-20-epi-vitamin D3 (1) by Pd(0)-catalyzed coupling between the boronate ester (2) and the enol triflate (3) is described. This article is part of a Special Issue entitled 'Vitamin D Workshop'.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
1α,25-Dihydroxyvitamin D3, ≥99% (HPLC)
Sigma-Aldrich
1α,25-Dihydroxyvitamin D3, ≥97.0% (HPLC)
Calcitriol, European Pharmacopoeia (EP) Reference Standard