SRP3298
BMP-4 mouse
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Synonym(e):
BMP-2B, DVR4
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)
About This Item
UNSPSC-Code:
12352202
NACRES:
NA.32
Empfohlene Produkte
Biologische Quelle
mouse
Rekombinant
expressed in E. coli
Assay
≥98% (HPLC)
≥98% (SDS-PAGE)
Form
lyophilized
Wirksamkeit
5-15 ng/mL ED50
Mol-Gew.
23.8 kDa
Verpackung
pkg of 10 μg
Verunreinigungen
<0.1 EU/μg endotoxin, tested
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Lagertemp.
−20°C
Angaben zum Gen
mouse ... BMP4(12159)
Allgemeine Beschreibung
The gene BMP4 (bone morphogenetic protein 4) encodes a member of the TGFβ (transforming growth factor β) superfamily of intercellular signaling proteins. It is found to be expressed in the extraembryonic ectoderm and mesoderm. E. coli derived murine BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor.
Anwendung
Bone morphogenetic protein 4 (BMP4) mouse has been used as an agonist for activin A receptor 1 (ALK2) receptors to test the effects of ALK2 activation in cell death.
Biochem./physiol. Wirkung
Bone morphogenetic protein 4 (BMP4) facilitates the the formation of allantois and primordial germ cell precursors in mouse embryo. It participates in hepatic specification in the early embryo. It is critical for the lens-inducing activity of optic vesicle in mouse embryo. BMP4 mediates atrioventricular septation of the mouse heart.
Physikalische Form
Lyophilized from 10 mM Citric Acid.
Rekonstituierung
Centrifuge the vial prior to opening. Reconstitute in 10 mM Citric Acid to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm.
Gouon-Evans V
Nature Biotechnology, 24, 1402-1411 (2006)
An essential role of Bmp4 in the atrioventricular septation of the mouse heart.
Jiao K
Genes & Development, 17, 2362-2367 (2003)
Flavio H Beraldo et al.
Journal of neurochemistry, 145(1), 68-79 (2017-12-22)
Stress-inducible phosphoprotein 1 (STI1) acts as a neuroprotective factor in the ischemic brain and its levels are increased following ischemia. Previous work has suggested that some of these STI1 actions in a stroke model depend on the recruitment of bone
Bmp4 is required for the generation of primordial germ cells in the mouse embryo.
Lawson KA
Genes & Development, 13, 424-436 (1999)
BMP4 is essential for lens induction in the mouse embryo.
Furuta Y and Hogan BL
Genes & Development, 12, 3764-3775 (1998)
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
Setzen Sie sich mit dem technischen Dienst in Verbindung.