Direkt zum Inhalt
Merck
Alle Fotos(2)

Key Documents

SRP0330

Sigma-Aldrich

BTK active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)

Synonym(e):

AGMX1, BPK, Bruton agammaglobulinemia tyrosine kinase, PSCTK1

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(2)

About This Item

CAS-Nummer:
391968-46-0
UNSPSC-Code:
12352204
NACRES:
NA.32

Biologische Quelle

human

Rekombinant

expressed in baculovirus infected Sf9 cells

Assay

≥80% (SDS-PAGE)

Form

aqueous solution

Mol-Gew.

106 kDa

Verpackung

pkg of 10 μg

Methode(n)

activity assay: suitable
inhibition assay: suitable

NCBI-Hinterlegungsnummer

NM_000061

UniProt-Hinterlegungsnummer

Q06187

Versandbedingung

dry ice

Lagertemp.

−70°C

Angaben zum Gen

human ... BTK(695)

Allgemeine Beschreibung

Human BTK (GenBank Accession No. NM_000061), full length with N-terminal GST-tag, MW= 106 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Anwendung

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

M Liljeroos et al.
Cellular signalling, 19(3), 625-633 (2006-10-06)
Lipoteichoic acid (LTA) of Gram-positive bacteria initiates innate immune responses via Toll-like receptor-2 (TLR2), resulting in the activation of intracellular signaling and production of inflammatory cytokines in macrophages. Although Bruton's tyrosine kinase (Btk) is biologically important molecule implicated in immune
L L Ong et al.
SLAS discovery : advancing life sciences R & D, 25(2), 176-185 (2019-11-12)
Protein kinases are intensely studied mediators of cellular signaling. While traditional biochemical screens are capable of identifying compounds that modulate kinase activity, these assays are limited in their capability of predicting compound behavior in a cellular environment. Here, we aim
Ximena Zottig et al.
The protein journal, 36(6), 478-488 (2017-10-05)
Recent investigations of Aneurinibacillus thermoaerophilus strains have allowed identification of a unique solvent tolerant lipase, distinct from known lipases. This work reports the expression and purification of this lipase (LipAT) and the first characterization of its structure and temperature and
Niklas Feldhahn et al.
The Journal of experimental medicine, 201(11), 1837-1852 (2005-06-09)
Pre-B cells undergo apoptosis unless they are rescued by pre-B cell receptor-dependent survival signals. We previously showed that the BCR-ABL1 kinase that is expressed in pre-B lymphoblastic leukemia bypasses selection for pre-B cell receptor-dependent survival signals. Investigating possible interference of
Miran Rada et al.
Oncotarget, 8(63), 106639-106647 (2018-01-02)
p53 is a tumour suppressor that is activated in response to various types of stress. It is regulated by a complex pattern of over 50 different post-translational modifications, including ubiquitination by the E3 ligase MDM2, which leads to its proteasomal
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.