SML3394

GZ-11608

≥98% (HPLC)

• Synonym(e): 4-​Methoxy-​N-​[(1S)​-​1-​methyl-​2-​phenylethyl]​-benzenepropanamine, S-3-(4-Methoxyphenyl)-N-(1-phenylpropan-2-yl)propan-1-amine
• Empirische Formel (Hill-System): C₁₉H₂₅NO
• CAS-Nummer: 2141974-01-6
• Molekulargewicht: 283.41
• UNSPSC-Code: 12352200
• NACRES: NA.21

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: oil
• Farbe: colorless to brown
• Lagertemp.: 2-8°C
• SMILES String: N([C@H](Cc2ccccc2)C)CCCc1ccc(cc1)OC
• InChIKey: LKTLDVZCNLGHOG-INIZCTEOSA-N

Beschreibung

Biochem./physiol. Wirkung

GZ-11608 is a potent and selective inhibitor of vesicular monoamine transporter-2 (VMAT2) that diminished hERG interaction. GZ-11608 reduces behavioral effects of methamphetamine such as locomotor activity, self-administration, and methamphetamine seeking behavior. It does not exhibit abuse liability. GZ-11608 inhibits methamphetamine-induced dopamine release from isolated synaptic vesicles from brain dopaminergic neurons.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable