SML1248

KT182

≥98% (HPLC)

• Synonym(e): [4-[3′-(Hydroxymethyl)[1,1′-biphenyl]-4-yl]-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-methanone
• Empirische Formel (Hill-System): C₂₇H₂₆N₄O₂
• CAS-Nummer: 1402612-62-7
• Molekulargewicht: 438.52
• MDL-Nummer: MFCD28118914
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825742
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 10 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: O=C(N1N=NC(C2=CC=C(C3=CC=CC(CO)=C3)C=C2)=C1)N4CCCCC4C5=CC=CC=C5
• InChI: 1S/C27H26N4O2/c32-19-20-7-6-10-24(17-20)21-12-14-22(15-13-21)25-18-31(29-28-25)27(33)30-16-5-4-11-26(30)23-8-2-1-3-9-23/h1-3,6-10,12-15,17-18,26,32H,4-5,11,16,19H2
• InChIKey: GICNKPZHUCVFNM-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

KT182 is a very potent, orally bioavailable, selective inhibitor of ABHD6 (a/b-Hydrolase Domain Containing 6). IC₅₀ = 1.7 nM. KT182 inhibits ABHD6 activity in the brain and liverin mice (ip administration).

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H413
• P-Sätze: P273 - P301 + P312 + P330
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Chronic 4
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable