SML0574

YM-298198 hydrochloride

≥98% (HPLC)

• Synonym(e): 6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride
• Empirische Formel (Hill-System): C₁₈H₂₂N₄OS · HCl
• CAS-Nummer: 1216398-09-2
• Molekulargewicht: 378.92
• MDL-Nummer: MFCD08703122
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825561
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: H₂O: 5 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: Cl.CN(C1CCCCC1)C(=O)c2sc3nc4ccc(N)cc4n3c2C
• InChI: 1S/C18H22N4OS.ClH/c1-11-16(17(23)21(2)13-6-4-3-5-7-13)24-18-20-14-9-8-12(19)10-15(14)22(11)18;/h8-10,13H,3-7,19H2,1-2H3;1H
• InChIKey: WYTJVUVCSUWZTH-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

YM-298198 is an orally active, noncompetitive mGlu1 receptor antagonist. The compound inhibits glutamate-induced inositol phosphate production in NIH3T3 cells (IC₅₀ = 16 nM). YM-298198 displays analgesic and antinociceptive properties in vivo.

Leistungsmerkmale und Vorteile

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable