SAB5701859

Anti-Phospho-TBK1/NAK-S172 antibody produced in rabbit

• UNSPSC-Code: 12352203
• NACRES: NA.43

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörper-Produkttyp: primary antibodies
• Klon: monoclonal
• Form: liquid
• Speziesreaktivität: mouse, human
• Konzentration: 0.74 mg/mL
• Methode(n): western blot: 1:500-1:2000
• UniProt-Hinterlegungsnummer: Q9UHD2
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer172)
• Angaben zum Gen: human ... TBK1(29110)

Beschreibung

Allgemeine Beschreibung

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]

Immunogen

A phospho specific peptide corresponding to residues surrounding S172 of human TBK1/NAK

Physikalische Form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable