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Key Documents

SAB4502603

Sigma-Aldrich

Anti-CYCLIN D1 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

BCL-1 oncogene, BCL1, CYL-1, G1/S-specific cyclin D1, cyclin D1

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About This Item

MDL-Nummer:
MFCD00239664
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 33 kDa

Speziesreaktivität

human, rat, mouse

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:5000
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

P24385

UniProt-Hinterlegungsnummer

P24385

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CCND1(595)

Allgemeine Beschreibung

Anti-CYCLIN D1 Antibody detects endogenous levels of total CYCLIN D1 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human Cyclin D1.

Immunogen Range: 56-105

Anwendung

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Adrian Krajewski et al.
Cancer management and research, 12, 13085-13097 (2020-12-31)
Cyclins are well-known cell cycle regulators. The activation of cyclin-dependent kinases by cyclins allows orchestration of the complicated cell cycle machinery and drives the cell from the G1 phase to the end of the mitotic phase. In recent years, it
Chao Tian et al.
OncoTargets and therapy, 13, 5353-5361 (2020-07-02)
MCTS1 re-initiation and release factor (MCTS1) is a ribosome-binding protein and shows multiple oncogenic properties in multiple cancers. This study aimed to investigate the expression, prognostic significance and transcription profile of MCTS1 in the PAM50 subtypes of breast cancer, as
Yü Liu et al.
Molecular medicine reports, 20(1), 125-134 (2019-05-23)
Interleukin enhancer‑binding factor 3 (ILF3) may function as a transcriptional coactivator and has been reported to be involved in tumor proliferation and metastasis; however, its role and clinical value in gastric cancer (GC) remains unclear. To understand the value of
Huaming Wei et al.
OncoTargets and therapy, 13, 13401-13411 (2021-01-08)
To investigate the effect of TRIM47 on glioma cells and further explore its underlying molecular mechanisms. Mouse xenograft model was used in this study. The mRNA expression of TRIM47 was detected by qRT-PCR. The cell viability and proliferation activity was
Xiangtai Wei et al.
Technology in cancer research & treatment, 13(1), 87-93 (2013-07-26)
Rhomboid domain containing 1 (RHBDD1) gene, a new member of rhomboid family of proteins is highly responsible for the regulation of apoptosis by cleaving pro-apoptotic Bcl-2 family protein BIK. Therefore, the higher expression levels of RHBDD1 in cancer tissues may
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