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Merck

SAB4501293

Sigma-Aldrich

Anti-GLUR1 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

GluR-1, GluR-A, GluR-K1, Glutamate receptor 1, Glutamate receptor ionotropic

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 101 kDa

Speziesreaktivität

human, mouse, rat

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... GRIA1(2890)

Verwandte Kategorien

Allgemeine Beschreibung

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) is located on human chromosome 5q33.2. It is expressed mainly in brain areas.

Immunogen

The antiserum was produced against synthesized peptide derived from human GluR1.

Immunogen Range: 816-865

Anwendung

Anti-GLUR1, C-Terminal antibody has been used in electron microscopy.

Biochem./physiol. Wirkung

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) plays an important role in long-term potentiation (LTP). It is associated with migraine.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Die Dokumentenbibliothek aufrufen

Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility
Formicola D, et al.
BMC Medical Genetics (2010)
Excitatory synaptic function and plasticity is persistently altered in ventral tegmental area dopamine neurons after prenatal ethanol exposure
Hausknecht K, et al.
Neuropsychopharmacology, 40(4), 893-905 (2015)
Selective disruption of stimulus-reward learning in glutamate receptor gria1 knock-out mice
Mead AN and Stephens DN
The Journal of Neuroscience, 23(3), 1041-1048 (2003)
Kathryn Hausknecht et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(4), 893-905 (2014-10-07)
Prenatal ethanol exposure (PE) is one of the developmental factors leading to increased addiction propensity (risk). However, the neuronal mechanisms underlying this effect remain unknown. We examined whether increased excitatory synaptic transmission in ventral tegmental area (VTA) dopamine (DA) neurons
Functional organization of the GluR1 glutamate receptor promoter
Borges K and Dingledine R
The Journal of Biological Chemistry, 276(28), 25929-25938 (2001)

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