SAB4500363

Anti-Collagen I α2 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): α 2 type i collagen, co1a2, col1a2, collagen, type i
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 129 kDa
• Speziesreaktivität: human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P08123
• UniProt-Hinterlegungsnummer: P08123
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... COL1A2(1278)

Beschreibung

Allgemeine Beschreibung

Anti-Collagen I α2 Antibody detects endogenous levels of total Collagen I α2 protein.

Collagen I α2 (COL1A2) is located on human chromosome 7q22.1. Human COL1A2 gene consists of two dinucleotide repeats: one in the 5′-flanking region of the gene, made of of poly(dC–dA) and poly(dC–dG) and the other in the first intron comprised of poly(dG–dT).

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen I alpha2.

Immunogen Range: 471-520

Anwendung

Anti-Collagen I α2 antibody has been used to quantify protein expression levels after western blotting.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Biochem./physiol. Wirkung

Collagen I α2 (COL1A2) is essential to maintain elasticity of the vessel wall and is an important constituent of the extracellular matrix. Mutations in COL1A2 results in osteogenesis imperfecta (OI).

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable